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Research Projects

PRACTICE ANALYTICS BROADER PROGRAMME CONTEXT The Practice Analytics program seeks to understand how hospitals can provide clinical teams and...

The JAK-STAT3 signaling pathway is engaged by many cytokines and growth factor stimuli to control diverse biological processes including...
Supervisor: Dr Daniel Gough

Pattern recognition receptors, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs) are key components of the innate immune response....
Supervisor: Dr Kate Lawlor

Severe asthma is difficult to manage clinically since it is often insensitive to high dose corticosteroid treatment, with patients typically...

TThe release of extracellular vesicles (EVs) is a property that has been conserved by both multi- and unicellular organisms during evolution. One of...

Pasteurella multocida is a Gram-negative bacterial pathogen that causes a number of different diseases in cattle, pigs and poultry, resulting in...

Detection of microbial components such as lipopolysaccharide (LPS) by Toll-like receptor (TLR)-4 expressed on macrophages induces a robust pro-...
Supervisor: Dr Daniel Gough

Our laboratory has for the first time identified a new NOD-like receptor (NLR) protein in the regulation of inflammation in response to chronic...

Mounting evidence suggests that neuronal activity influences myelination, potentially allowing for experience-driven modulation of neural circuitry....
Supervisor: Dr Tobias Merson

Diffuse Intrinsic Pontine Glioma is a highly aggressive cancer that arises in the brainstem of children and is universally fatal. Using next-...
Supervisor: Dr Jason Cain

CRISPR-Cas9 gene editing has revolutionised our vision of the genome, which can now be edited to correct mutations, or silence aberrant genes. The...
Supervisor: Dr Michael Gantier

Description: Protein arginine methyltransferases (PRMTs) are a family of 11 enzymes that methylate arginines in a broad range of proteins including...

Delerium is a common and disturbing symptom for palliative care patients. This prospective research will look at the factors and causes of delerium,...

Audit and feedback (A&F) is a method for improving clinical practice in line with evidence-based recommendations and supporting translation of...
Supervisor: Dr Denise O'Connor

Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...

Associate Professor Kazantzis is interested in working with motivated honours students who want to learn more about how to practice Cognitive...

Individuals that lack a normal functioning immune system are susceptible to opportunistic infections when challenged by pathogens (e.g viruses and...
Supervisor: Dr George Grigoriadis

Well-conducted individually randomised trials are the gold standard for establishing whether a particular intervention is effective, but when...
Supervisor: Dr Jessica Kasza

Partially clustered trials involve the collection of partially clustered data, where some observations are independent and other observations are...
Supervisor: Dr Jessica Kasza

The interrupted time series (ITS) study design is frequently used to evaluate the effects of policy and health systems interventions, providing...
Supervisor: Dr Joanne McKenzie

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