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Research Projects

Lung cancer patient's die from metastatic disease, not primary disease. In the case of small cell lung cancer the brain is a primary site of...
Supervisor: A/Prof Daniel Gough

Osteosarcoma is the most prevalent primary bone tumour, with a predominance in children and adolescents in periods of rapid growth. Despite...
Supervisor: A/Prof Jason Cain

Epigenetics provides an interface between the environment and DNA function through the ability of epigenetic modifications to regulate gene...

Pattern recognition receptors, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), are key components of the innate immune response....

The World Mosquito Program (WMP; based at Monash University) has pioneered a novel biocontrol tool, Wolbachia, that controls the transmission of...
Supervisor: Dr. Johanna Fraser

Antigen presentation is the fundamental and complex process in which a cell breaks down proteins into small fragments (peptides) and presents these...
Supervisor: Chen Li

Gastric cancer kills ~1 million people worldwide each year and has an average 5-year survival rate of 19%. It is, therefore, a cancer of unmet need....
Supervisor: Dr Dustin Flanagan

It is well-known that cancer treatments damage eggs in the ovary to impair fertility. However, the impacts of different cancer treatments on the...
Supervisor: Dr Amy Winship

Osteosarcoma is the most prevalent primary malignant tumour of the bone, mainly affecting teenagers and young adults, particularly during growth...
Supervisor: A/Prof Jason Cain

Pasteurella multocida is a Gram-negative bacterial pathogen that causes a number of different diseases in cattle, pigs and poultry, resulting in...

Our laboratory has for the first time identified a new NOD-like receptor (NLR) protein in the regulation of inflammation in response to chronic...

Brain tumours are highly immunosuppressed, which has meant that they are uniquely resistant to immunotherapies. Importantly, T cell infiltration into...
Supervisor: Leon Smyth

The mRNA therapeutics have emerged as a high potent new class of drug, revolutionizing disease treatments, such as therapeutic vaccines, monoclonal...

The ADNeT Registry a clinical quality registry (CQR) for people newly diagnosed with either dementia or mild cognitive impairment (MCI). The registry...
Supervisor: Dr Xiaoping Lin

Through leveraging extensive longitudinal data and biospecimens already obtained from a large representative cohort of older Australians, this...
Supervisor: Professor Joanne Ryan

Genome-wide association studies (GWAS) have been instrumental in discovering these loci, and they have successfully identified numerous disease-...
Supervisor: Dr Sathish Periyasamy

Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...

The contraceptive pill has been linked to depressive mood. It has been hypothesised that the progesterone components of the pill are likely to drive...

There are over 7,000 rare diseases that on average take ~4 years to diagnose, during which families consult on average 5 doctors and receive 3...

This summer scholarship project involves working with a researcher, people living with dementia and care partners on a project to design a dementia...
Supervisor: Dr Marianne Coleman

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