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Computational Analysis of NK Cell Activity and Cancer Cell Immunogenicity in Solid Tumours

Description 
Natural killer (NK) cell activity is essential for initiating antitumor responses and may be linked to immunotherapy success. NK cells and other innate immune components could be exploitable for cancer treatment, which drives the need for tools and methods that identify therapeutic avenues. The gene-set scoring method singscore can be used to investigate NK cell infiltration by applying RNA-seq analysis to samples from bulk tumors. Computational methods have been developed for the deconvolution of immune cell types within solid tumors.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Transcriptomics; NK Cell; Immunotherapy
Available options 
PhD/Doctorate
Masters by research
Honours
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
No
Physical location 
15 Innovation Walk
Co-supervisors 
Dr 
Momeneh Foroutan

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