Research Projects
Mitochondria are essential for metabolism, signalling, and adaptation, yet the molecular basis for their extraordinary diversity remains poorly...
Supervisor: Associate Professor James Letts
Single-cell analyses are at the leading edge of technological development for cell biology. And, transcriptomics analyses at single-cell resolution...
Supervisor: Prof Traude Beilharz
Background: Cell-based therapeutics have made advances in recent years. One of the most clinically studied products in regenerative medicine is...
Supervisor: Associate Professor Tracy Heng
Obesity is an enormous health concern, both in Australia and worldwide. Our laboratory recently published a function for the ETS-5 transcription...
Supervisor: Professor Roger Pocock
Anorexia nervosa (AN) is characterised by extreme self-control, partly generated by exaggerated prefrontal cortex activity, which leads to inflexible...
Supervisor: Dr Claire Foldi
Project Overview
Billions of cells die every day and must be efficiently removed to maintain tissue health. While the clearance of apoptotic cells...
Supervisor: Dr Denuja Karunakaran
Immunotherapies have transformed the treatment of many cancers, but not prostate cancer. Chimeric-antigen receptor (CAR) T cell therapy, in which a...
Supervisor: Dr Laura Porter
Acinetobacter baumannii has been identified as one of the top three dangerous Gram-negative hospital pathogens as it can cause a range of life-...
Supervisor: Assoc Professor John Boyce
Our research program is focused on fibroblast-like stromal cells found in secondary lymphoid organs and tumours. These cells create the structure on...
Supervisor: Dr Anne Fletcher
Background:
Our group is involved in an Australia-wide program (www.kidgen.org.au) which aims to identify novel causative genes in patients with...
Supervisor: Assoc Professor Ian Smyth
Characterising novel virulence mechanisms in the emerging hospital-acquired pathogen;
Acinetobacter baumannii
(A/Professor John Boyce, Dr Faye...
Supervisor: Assoc Professor John Boyce
It is now well-established that the cancer stroma, including cancer-associated fibroblasts, plays a major role in development and progression of this...
Supervisor: Professor Roger Daly
Given their natural adjuvant properties, and their unique attributes in promoting T cell priming and recruitment into solid tumors, dendritic cells (...
Supervisor: MICHAEL CHOPIN, PHD
Natural products are structurally interesting molecules (metabolites) produced in nature by organisms such as bacteria, fungi and plants. The unique...
Supervisor: Dr. Lauren Murray
Chronic pain is a major global health burden, affecting nearly 20% of the Australian population. This debilitating condition results in...
Supervisor: Professor Wendy Imlach
The identification of genetic, environmental and lifestyle factors that contribute to breast cancer susceptibility has had a marked impact on breast...
Supervisor: Professor Joseph (Sefi) Rosenbluh
It is now well appreciated that adipocytes are not simply fat storage cells, but can be subdivided into white, brown and ‘beige’ cells, with the...
Supervisor: Professor Tony Tiganis
A central focus of this project is the study of evasins, a family of proteins found in tick saliva that bind to and inhibit multiple chemokines,...
Supervisor: Dr Ram Bhusal
Natural killer (NK) cell activity is essential for initiating antitumor responses and may be linked to immunotherapy success. NK cells and other...
Supervisor: Professor Nicholas Huntington
The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...
Supervisor: Professor John Carroll