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Research Projects

We have identified specific insulins that act in the brain to control animal behaviour. This exciting project will use genetics, CRISPR, behavioural...

The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...

Stem cell therapy holds immense potential as a treatment paradigm for a number of conditions. However, currently the therapeutic outcome is often...
Supervisor: Dr Mark Del Borgo

During the last decades, substantial advances have been made in the various ‘omics techniques’ (such as transcriptomics, proteomics, metabolomics and...
Supervisor: Dr Ralf Schittenhelm

Cryo-electron tomography (CET) allows for the highest resolution cellular imaging possible at the moment. To get access to all areas of the cell we...
Supervisor: Dr Georg Ramm

Pasteurella multocida is a Gram-negative bacterial pathogen that causes a number of different diseases in cattle, pigs and poultry, resulting in...

Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...

This project aims to design, synthesize and evaluate a novel class of oligonucleotides. Oligonucleotides have emerged as a revolutionary tool in...
Supervisor: Dr Nitin Patil

Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...

The malaria parasite Plasmodium falciparum employs metallo-aminopeptidase enzymes (PfMAP) that are required for parasite survival. Three of these...
Supervisor: Dr Sheena McGowan

Type 2 diabetes (T2D) is highly prevalent, with an estimated 370 million affected individuals worldwide, and this is predicted to double by 2030....
Supervisor: Professor Colby Zaph

Fibrosis is defined as the hardening and/or scarring of various organs including the heart and kidney, which usually results from abnormal wound...

Current clinical management of obstructive sleep apnoea (OSA), a common sleep disorder, uses constant positive airway pressure as first-line...
Supervisor: Dr Brad Edwards

We have recently discovered a very potent antibody targeting the chemokine receptor CXCR3, a promising target for the treatment of inflammatory and...
Supervisor: Dr Remy Robert

The Monash Vision Group is developing a cortical vision prosthesis to restore vision to the blind. We currently have various projects focussed around...
Supervisor: Dr Yan Wong

The project aims to develop and deploy to the scientific community a robust method to target and isolate discrete regions within a frozen biological...

The growing problem of antibiotic resistance underlies the critical need to develop new treatments to prevent and control resistant bacterial...
Supervisor: Dr Sheena McGowan

Adaptive optics (AO) are used to improve the performance of optical systems. Through the use of AO, it is possible to compensate for any distortion...

Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease resulting in the destruction of the insulin-producing beta cells in the pancreas. T1D...

The functions of at least half of the proteins encoded in the genome of Plasmodium falciparum malaria parasites remain unknown. Understanding protein...
Supervisor: Professor Brian Cooke

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