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Research Projects

This project will investigate the machinery involved in mitochondrial fission and fusion and the relationship between mitochondrial dynamics and...
Supervisor: Professor Mike Ryan

Background: Our group is involved in an Australia-wide program (www.kidgen.org.au) which aims to identify novel causative genes in patients with...

Characterising novel virulence mechanisms in the emerging hospital-acquired pathogen; Acinetobacter baumannii (A/Professor John Boyce, Dr Faye...

It is now well-established that the cancer stroma, including cancer-associated fibroblasts, plays a major role in development and progression of this...
Supervisor: Professor Roger Daly

Given their natural adjuvant properties, and their unique attributes in promoting T cell priming and recruitment into solid tumors, dendritic cells (...
Supervisor: MICHAEL CHOPIN, PHD

Langerhans cells are specialized dendritic cells localized in the skin, and exclusively express CD1a on the cell surface. CD1a presents lipids found...
Supervisor: Dr Adam Shahine

Natural products are structurally interesting molecules (metabolites) produced in nature by organisms such as bacteria, fungi and plants. The unique...
Supervisor: Dr. Lauren Murray

Chronic pain is a major global health burden, affecting nearly 20% of the Australian population. This debilitating condition results in...
Supervisor: Dr Wendy Imlach

It is now well appreciated that adipocytes are not simply fat storage cells, but can be subdivided into white, brown and ‘beige’ cells, with the...

We have discovered that the initiation of a TCR signal in Treg cells entails docking of the Treg TCR in the opposite orientation to that observed for...
Supervisor: Dr Hugh Reid

Protein folding stability is a fundamental property that determines whether a protein adopts its functional three-dimensional structure or remains...
Supervisor: Dr Ram Bhusal

Natural killer (NK) cell activity is essential for initiating antitumor responses and may be linked to immunotherapy success. NK cells and other...

The PI3K-Akt-mTOR signalling network plays a pivotal role in the regulation of cell growth and proliferation, and is highly complex with multiple...
Supervisor: Dr Lan Nguyen

Sense of touch (somato-sensation) becomes available to embryos even before birth and is one of the oldest senses in the animal kingdom, yet little is...
Supervisor: Dr Mehdi Adibi

The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...

The underlying cause of coronary artery disease (CAD) is atherosclerosis – a maladaptive inflammatory condition driven primarily by macrophages,...
Supervisor: Dr Denuja Karunakaran

The aim of this multidisciplinary project is to design techniques and build low-cost, efficient automated solutions for behavioural study in rodents...
Supervisor: Dr Mehdi Adibi

Neuroscience is becoming an exciting and multidisciplinary field, with a combination of biology, psychology, engineering, and large-data processing....
Supervisor: Dr Tatsuo Sato

Cryo-electron tomography (CET) allows for the highest resolution cellular imaging possible at the moment. To get access to all areas of the cell we...
Supervisor: Dr Georg Ramm

This ARC funded project will decipher the mechanism(s) underpinning the rapid and extensive membrane remodelling in the Gram-negative bacteria...
Supervisor: Dr Meiling Han

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