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Research Projects

Natural products are structurally interesting molecules (metabolites) produced in nature by organisms such as bacteria, fungi and plants. The unique...
Supervisor: Dr. Lauren Murray

It is now well appreciated that adipocytes are not simply fat storage cells, but can be subdivided into white, brown and ‘beige’ cells, with the...

Natural killer (NK) cell activity is essential for initiating antitumor responses and may be linked to immunotherapy success. NK cells and other...

The PI3K-Akt-mTOR signalling network plays a pivotal role in the regulation of cell growth and proliferation, and is highly complex with multiple...
Supervisor: Dr Lan Nguyen

Cryo-electron tomography (CET) allows for the highest resolution cellular imaging possible at the moment. To get access to all areas of the cell we...
Supervisor: Dr Georg Ramm

Gastric cancer kills ~1 million people worldwide each year and has an average 5-year survival rate of 19%. It is, therefore, a cancer of unmet need....
Supervisor: Dr Dustin Flanagan

Brain tumours are highly immunosuppressed, which has meant that they are uniquely resistant to immunotherapies. Importantly, T cell infiltration into...
Supervisor: Leon Smyth

The mRNA therapeutics have emerged as a high potent new class of drug, revolutionizing disease treatments, such as therapeutic vaccines, monoclonal...

Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...

Join the Monash Proteomics and Metabolomics Platform (MPMP) metabolomics team for an exciting summer project to improve retention time (RT)...
Supervisor: Dr. Katy Jeppe

Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...

We have recently discovered a very potent antibody targeting the chemokine receptor CXCR3, a promising target for the treatment of inflammatory and...
Supervisor: Dr Remy Robert

Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, metabolic diseases, and cancer. Namely,...
Supervisor: Dr Wael Awad

The most aggressive forms of prostate cancer demonstrate resistance to multiple types of cancer drugs. We have performed RNA-sequencing on a large...
Supervisor: Dr David Goode

Chronic infectious diseases have a devastating effect on global health. HIV and Plasmodium falciparum both cause chronic disease and have evaded...

RESEARCH PROJECT BACKGROUND: The endocrine system controls cell-cell communication and coordinates almost all our daily activities. Abnormalities in...

Vaccines exploit the ability of the immune system to provide heightened, tailored responses to pathogens if the host has been infected prior – this...

We wish to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co‐factor...

Preliminary data from the Nguyen-Daly lab has identified Fibroblast growth factor receptors (FGFRs) as promising therapeutic targets for triple-...
Supervisor: Dr Lan Nguyen

Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, metabolic diseases, and cancer. Namely,...
Supervisor: Dr Wael Awad

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