Research Projects
Transcription factors (TFs) are key proteins that regulate gene expression by binding to specific regions of the genome known as regulatory elements...
Supervisor: Dr Anja Knaupp
Cancer immunotherapy has revolutionised the treatment of many cancers, but this potentially effective treatment can also cause significant side-...
Supervisor: Dr Miles Andrews
Lung cancer patient's die from metastatic disease, not primary disease. In the case of small cell lung cancer the brain is a primary site of...
Supervisor: A/Prof Daniel Gough
Osteosarcoma is the most prevalent primary bone tumour, with a predominance in children and adolescents in periods of rapid growth. Despite...
Supervisor: A/Prof Jason Cain
Epigenetics provides an interface between the environment and DNA function through the ability of epigenetic modifications to regulate gene...
Supervisor: Professor Patrick Western
Pattern recognition receptors, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), are key components of the innate immune response....
Supervisor: Associate Professor Kate Lawlor
The World Mosquito Program (WMP; based at Monash University) has pioneered a novel biocontrol tool, Wolbachia, that controls the transmission of...
Supervisor: Dr. Johanna Fraser
Antigen presentation is the fundamental and complex process in which a cell breaks down proteins into small fragments (peptides) and presents these...
Supervisor: Chen Li
Gastric cancer kills ~1 million people worldwide each year and has an average 5-year survival rate of 19%. It is, therefore, a cancer of unmet need....
Supervisor: Dr Dustin Flanagan
It is well-known that cancer treatments damage eggs in the ovary to impair fertility. However, the impacts of different cancer treatments on the...
Supervisor: Dr Amy Winship
Osteosarcoma is the most prevalent primary malignant tumour of the bone, mainly affecting teenagers and young adults, particularly during growth...
Supervisor: A/Prof Jason Cain
Pasteurella multocida is a Gram-negative bacterial pathogen that causes a number of different diseases in cattle,
pigs and poultry, resulting in...
Supervisor: Assoc Professor John Boyce
Our laboratory has for the first time identified a new NOD-like receptor (NLR) protein in the regulation of inflammation in response to chronic...
Supervisor: Professor Richard Ferrero
Brain tumours are highly immunosuppressed, which has meant that they are uniquely resistant to immunotherapies. Importantly, T cell infiltration into...
Supervisor: Leon Smyth
The mRNA therapeutics have emerged as a high potent new class of drug, revolutionizing disease treatments, such as therapeutic vaccines, monoclonal...
Supervisor: Nanoantibiotics - SHEN LAB
The ADNeT Registry a clinical quality registry (CQR) for people newly diagnosed with either dementia or mild cognitive impairment (MCI). The registry...
Supervisor: Dr Xiaoping Lin
Genome-wide association studies (GWAS) have been instrumental in discovering these loci, and they have successfully identified numerous disease-...
Supervisor: Dr Sathish Periyasamy
Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...
Supervisor: Assoc Professor Meredith O'Keeffe
The contraceptive pill has been linked to depressive mood. It has been hypothesised that the progesterone components of the pill are likely to drive...
Supervisor: Professor Jayashri Kulkarni
There are over 7,000 rare diseases that on average take ~4 years to diagnose, during which families consult on average 5 doctors and receive 3...
Supervisor: Professor Katrina Williams