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Research Projects

Project Overview: In the ever-evolving realm of immunology, the enigmatic world of non-canonical Human Leukocyte Antigen (HLA)-bound peptides...
Supervisor: Dr Pouya Faridi

A major challenge in cancer therapeutics is to kill tumour cells without harming normal cells in the body. Traditional chemotherapy tries to do this...
Supervisor: Dr Lan Nguyen

Preterm birth is a public health concern, and it has been listed as one of the focuses under the Good Health and Well-Being of The Sustainable...
Supervisor: Dr Jodi Law Woan-Fei

The Next Generation Precision Medicine Program focuses on utilising genetic profiles of patients’ tumour models to identify new therapeutic targets...
Supervisor: Dr Claire Sun

The project: Antigen presenting cells (APCs) play a crucial role in establishing and maintaining an immune response towards cancer cells. In recent...

Psoriasis is a skin autoimmune disease that affects 2-3% of the global population. Around half of the patients carry the major risk gene for...
Supervisor: Dr. Asolina Braun

RNA sequencing technologies enable the simultaneous detection of tens of thousands of genes, providing researchers with a powerful tool for...
Supervisor: Professor Wei Shi

Single-cell analyses are at the leading edge of technological development for cell biology. And, transcriptomics analyses at single-cell resolution...

Endometriosis is a chronic disease characterised by growth of cells in ectopic locations and chronic inflammation. This project looks to 1)...
Supervisor: Dr Fiona Cousins

The microbial communities associated with every surface of our bodies are incredibly diverse, yet we know practically nothing about the majority of...

Natural products are structurally interesting molecules (metabolites) produced in nature by organisms such as bacteria, fungi and plants. The unique...
Supervisor: Dr. Lauren Murray

Genetic variants have been found to cause epilepsy as well as affect how people respond to treatment. Whole exome sequencing is a new method of...

Anorexia nervosa (AN) has clear biological underpinnings, however, the molecular mechanisms that lead to the development of this debilitating...
Supervisor: Dr Claire Foldi

Androgen deprivation therapy (ADT) is an important last-line treatment for advanced prostate cancer. ADT initially works well but eventually fails in...
Supervisor: Dr Renea Taylor

Enduring antibody-mediated immunity is critical for vaccines to provide protection from infectious disease. Despite the success of vaccines to date,...
Supervisor: Dr Danika Hill

Antimicrobial resistance (AMR) is emerging at an alarming level, rendering some bacterial infections untreatable and increasing dependence on last...

We and many others over the last few decades have contributed to a now much improved understanding of the genomic components of familial risk for...

The most aggressive forms of prostate cancer demonstrate resistance to multiple types of cancer drugs. We have performed RNA-sequencing on a large...
Supervisor: Dr David Goode

Current therapies for epilepsy are symptomatic, only suppressing the symptoms (seizures), but do not impact the development or progression of disease...

Conventional chemotherapeutic agent, temozolomide (TMZ), for Glioblastoma (GBM) often displays high chemoresistance with various side effects....
Supervisor: Alfarizal Kamarudin

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