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Research Projects

Obstructive sleep apnoea (OSA) is characterized by repetitive collapse (apnoea) or partial collapse (hypopnoea) of the pharyngeal airway during sleep...

The Mediator complex with its catalytic subunit the Mediator kinase module, composed of CDK8/19 and other members, is multimeric complex regulating...
Supervisor: Dr Marius Dannappel

HIV infection has a substantial impact on immune cells, and whilst many of these effects are improved after starting anti-HIV therapy, they are often...
Supervisor: Dr Anna Hearps

Self-reactive T cells cause many autoimmune diseases, and can also trigger serious autoimmune side-effects in cancer patients undergoing...

We manage the Australian Autoinflammatory Disease Registry (AADRY.org), and collaborate widely to identify genetic variants that may be the cause of...
Supervisor: Prof Seth Masters

Incomplete reporting of systematic reviews prevents users of the report from being able to fully interpret the findings and understand the...
Supervisor: Dr Matthew Page

Inflammatory Bowel Disease (IBD), predominantly Crohn’s Disease (CD) and Ulcerative Colitis (UC), is a chronic inflammatory condition of unknown...
Supervisor: A/Prof Edward Giles

Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly

Congenital syphilis, caused by mother to child transmission of syphilis, is the second leading cause of stillbirth globally. Definitive diagnosis of...
Supervisor: Dr Minh Pham

As malaria transmission continues to decline, even the most sensitive methods for determining prevalence via detection of the parasite become...

Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose

Wet Lab based projects (full for 2025-2026, possible 2026-2027 Novel stem cell therapies in stroke

Stroke is a global leading cause of death and disability. Despite this, there is currently no treatment to limit inflammatory events which has been...
Supervisor: Professor Connie Wong

The formation of the head and face is a tightly regulated process, with variations from the genetic program leading to craniofacial defects. We have...
Supervisor: Dr. Jan Manent

Parkinson's disease (PD) is a debilitating neurodegenerative disorder that affects over 7 million people worldwide. Hallmark symptom of PD is...
Supervisor: Dr Joohyung Lee

Cardiovascular diseases (CVDs), principally ischemic heart disease including myocardial infarction (heart attacks) and stroke, are the leading cause...

One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...

Background: Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence and is associated with high morbidity and mortality...

Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott

Women are recommended to have a 6-8 postnatal check after having a baby, usually with their general practitioner (GP). Whilst there is an expectation...
Supervisor: Dr Jessica Botfield

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