Research Projects
People with underlying non-communicable disease have lower tolerance and worse outcomes to infections but we don't understand why. To begin to...
Supervisor: Dr Adam Rose
Studies in T cell mediated immunity have focused on understanding the presentation of peptides by the Major Histocompatibility Complex (MHC), and...
Supervisor: Dr Jerome Le Nours
Mitochondria are key players in health and disease. They are the main source of energy in eukaryotic cells, oxidizing sugars and fats to generate ATP...
Supervisor: Professor Mike Ryan
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
Background:
The innate immune system senses and responds to endogenous and exogenous danger signals in order to protect the host. cGAMP synthase (...
Supervisor: Dr Dominic De Nardo
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
This project will explore the human T cell receptor molecular recognition of mycobacterial lipid antigens presented by CD1b. These lipids are unique...
Supervisor: Dr Adam Shahine
Cytomegaloviruses (CMV) are a family of species-specific viruses that have evolved sophisticated strategies to interfere with host immunity, thereby...
Supervisor: Dr Richard Berry
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
This project centres on KIR3DL1 polymorphism and how it translates to improved outcomes in hematopoietic stem cell transplantation for the treatment...
Supervisor: Mr Julian Vivian
Many bacteria are motile. Chemotaxis, mediated by chemoreceptors, plays an important role in bacterial survival and virulence. In this project, we...
Supervisor: Assoc Professor Anna Roujeinikova
Gram-negative bacteria have caused substantial multi-drug resistance (MDR) in both clinical and community settings. Antimicrobial peptides (AMPs),...
Supervisor: Nanoantibiotics - SHEN LAB
Some intermediary metabolic enzymes are upregulated in the liver of mice and humans with type 2 diabetes. Here we will test whether and how these...
Supervisor: Dr Adam Rose
Tumours lose features of multicellularity, such as tissue differentiation and coordinated cell division, and start to resemble colonial unicellular...
Supervisor: Dr David Goode
This project uses spatial proteomics and transcriptomics data to map locations of immune cells within the vicinity of paediatric and adult brain...
Supervisor: Dr David Goode
Antibiotic resistance continues to emerge and intensify. Antimicrobial peptides (AMPs) are a promising alternative to current antibiotics, but...
Supervisor: Professor Mibel Aguilar
Unlike other infections in which one single encounter with the pathogen is enough to induce long-lasting protection, immunity to malaria might take...
Supervisor: Prof Diana Hansen
We develop methods for single particle electron microscopy (SPEM). Our SPEM developments are motivated by our interest in transcriptional control...
Supervisor: Dr Dominika Elmlund
Our vision: "driving excellence in medical research to build a healthier future"
Our research centres on an exciting development in...
Supervisor: Dr Eliana Marino Moreno
Studies from lower order organisms such as flies and worms have shown that mild mitochondrial dysfunction invokes a stress response that promotes...
Supervisor: Dr Adam Rose