Research Projects
The enigmatic receptor KIR2DL5.
KIR2DL5 is the least understood member of the KIR family. By sequence, KIR2DL5 is a hybrid of KIR3DL1 (see Vivian...
Supervisor: Mr Julian Vivian
The presentation of post-translationally modified (PTM) peptides by cell surface MHC molecules increases the diversity of targets for recognition by...
Supervisor: Dr Nathan Croft
Our studies provide validation that the impact of dietary metabolites within the gut has local as well as far-reaching anti-inflammatory effects on...
Supervisor: Dr Eliana Marino Moreno
Malaria is one of the most devastating infectious diseases worldwide, causing major public health, social and economic problems globally. The lack of...
Supervisor: Professor Christian Doerig
It is well-established that neurons in the whisker area of somatosensory cortex and thalamus exhibit directional selectivity. Direction preference is...
Supervisor: Dr Mehdi Adibi
Our mothers programed the first decisions of our lives by mRNA dumping: the regulated translation of this maternal transcriptome controls the first...
Supervisor: A/Prof Traude Beilharz
Monoclonal antibodies (mAbs) that block checkpoint inhibitory receptors including Programmed Death (PD)-1 act directly on T cells to overcome ‘...
Supervisor: Assoc Professor Meredith O'Keeffe
Recently, novel genetic variants of GPR75 were discovered to be associated with leanness in large genome wide associated studies. This is the first...
Supervisor: Professor Zane Andrews
All living things respond to changes in their direct environment by evoking innate stress response mechanisms. Multiple factors, including those...
Supervisor: Dr Kylie Wagstaff
Chronic kidney disease CKD is an inflammatory condition that is increasing in prevalence around the world. Diabetes and obesity are the primary cause...
Supervisor: Dr Eliana Marino Moreno
This study investigates the role of Smad3 acetylation in the development and progression of organ/tissue fibrosis.
Supervisor: Assoc Professor Jinhua Li
Small noncoding RNAs are increasingly recognised as important regulators of gene expression and genome integrity across all kingdoms of life. This is...
Supervisor: Dr Peter Boag
The tyrosine kinase Src was the first proto-oncogene to be identified, and it is now known that Src plays an important role in several human cancers...
Supervisor: Professor Roger Daly
Dysfunctional feeding behaviour encompasses energy overconsumption (obesity, binge eating) to malnutrition (unhealthy food choices, excessive dieting...
Supervisor: Professor Zane Andrews
Heme is an essential nutrient for the bacterial pathogen Haemophilus influenzae, which causes serious respiratory infections, otitis media and...
Supervisor: Dr Rhys Grinter
We are performing in-depth characterization of the microenvironment of human tumours, and discovering new mechanisms used by these cells to influence...
Supervisor: Dr Anne Fletcher
The oocyte-secreted TGF-beta proteins, BMP15 and GDF9, are essential for the acquisition of oocyte developmental competence during folliculogenesis....
Supervisor: Assoc Professor Craig Harrison
The oocyte-secreted factors, bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9), are essential for the acquisition of...
Supervisor: Dr Kelly Walton
The thymus is primarily responsible for generating naïve, self-tolerant T cells from hematopoietic precursors. However, deterioration of thymic...
Supervisor: Assoc Professor Ann Chidgey