Description
The tyrosine kinase Src was the first proto-oncogene to be identified, and it is now known that Src plays an important role in several human cancers, including those of the breast, colon and pancreas. Our laboratory has utilized a novel mass spectrometry-based approach to identify protein kinases that respond to Src activation, and then functional screens to determine which ones are critical for cancer cell growth. This project will utilize several approaches, including siRNA knockdowns and assays for cell proliferation, migration and morphology, to determine in detail how these protein kinases contribute to Src-regulated oncogenesis.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
Cancer, protein kinases, Department of Biochemistry & Molecular Biology
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Biochemistry and Molecular Biology
Available options
PhD/Doctorate
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Clayton Campus
Research webpage