Research Projects
        Impact of pregnancy on long-term outcomes in women with multiple sclerosis – assessment of mechanism  
  
  Data suggests that pregnancy in women with multiple sclerosis (MS) may exert long-term health benefits.  Comparisons of women with and without...
      Supervisor:     Associate Professor Vilija Jokubaitis  
  
  Tumours are a highly heterogeneous mix of multiple cellular subpopulations, each with their own unique molecular and biological properties. Studying...
      Supervisor:     Dr Renea Taylor  
  
  This project is part of the RNA Systems Biology Lab's ambition to de-risk discovery and translational research using a novel RNA-seq based...
      Supervisor:     Prof Traude Beilharz  
  
  Brain energetics during gestation is a fundamental mechanism of neurodevelopment. Compared to the adult brain, brain energy metabolism in the fetus (...
      Supervisor:     Dr Stacey Ellery  
  
  The interplay between genotype and phenotype is governed by a multitude of genetic interactions (GIs), and the mapping of GI networks holds...
      Supervisor:     Dr Sathish Periyasamy  
  
  Lung cancer is the second most common cancer in both men and woman, and non-small cell lung cancer accounts for 80% of lung cancer cases. Across...
      Supervisor:     A/Prof Vivek Naranbhai  
  
  Tumours lose features of multicellularity, such as tissue differentiation and coordinated cell division, and start to resemble colonial unicellular...
      Supervisor:     Dr David Goode  
  
  Cancer follows an evolutionary process shaped by the environment of the tumour. Deciphering which genes and processes enable tumour cells to adapt to...
      Supervisor:     Dr David Goode  
  
  This project uses spatial proteomics and transcriptomics data to map locations of immune cells within the vicinity of paediatric and adult brain...
      Supervisor:     Dr David Goode  
  
  This project is suitable for Honours or Masters (modified version) and PhD students.
Background:
Acute myeloid leukaemia (AML) is an aggressive...
      Supervisor:     Dr Claudia Bruedigam  
  
  Advances in single-cell and spatial transcriptomics are transforming the study of gene regulation and cellular function. Single-cell RNA sequencing...
      Supervisor:     Professor Wei Shi  
  
  The innate immune system is capable of intricately detailed detection, differentiation and elimination of pathogenic bacteria. However,  the vast...
      Supervisor:     Assoc Prof Sam Forster  
  
  A central feature of inflammatory diseases is the migration of white blood cells into the affected tissues. This is controlled by a group of proteins...
      Supervisor:     Assoc Professor Martin Stone  
  
  Despite enormous progress in research, cancer remains a devastating disease worldwide. Since generally not all patients will respond to a specific...
      Supervisor:     Dr Lan Nguyen  
  
  Industry-Academia PhD Position
New tools for immunopeptidomics 
An opportunity for an outstanding PhD candidate to undertake a collaborative...
      Supervisor:     Professor Anthony Purcell  
  
  HIV infection has a substantial impact on immune cells, and whilst many of these effects are improved after starting anti-HIV therapy, they are often...
      Supervisor:     Dr Anna Hearps  
  
  The formation of the head and face is a tightly regulated process, with variations from the genetic program leading to craniofacial defects. We have...
      Supervisor:     Dr. Jan Manent  
  
  In collaboration with Monash Health, Victorian Heart Hospital and Victorian Heart Institute, we are seeking a medical, nursing or an allied health...
      Supervisor:     Adj Assoc Prof Peter Poon  
  
  Multiple sclerosis, an autoimmune, neurodegenerative condition, is the most common cause of non-traumatic neurological disability in young adults....
      Supervisor:     Associate Professor Vilija Jokubaitis  
  
  Mainstream anti-epileptic drugs (AEDs) that are used to treat epilepsy and some other conditions are associated with a range of cutaneous side...
      Supervisor:     Professor Patrick Kwan  
  
  