Research Projects
We wish to revolutionise the treatment of autoimmune diseases. We are hoping to devise strategies to eliminate harmful auto reactive cells using...
Supervisor: Professor Charles Mackay
Helicobacter pylori persistently colonize the epithelium of the stomach in roughly half of the world’s population. It is a causative agent of...
Supervisor: Assoc Professor Anna Roujeinikova
The LCT-producing clostridia are an important group of pathogens that cause severe disease in both humans and animals. In most cases the diseases...
Supervisor: Professor Dena Lyras
This project investigates the novel architecture of the power system found in a bacterial flagellar motor specialised for locomotion in viscous...
Supervisor: Assoc Professor Anna Roujeinikova
A cardinal feature of adaptive CD8+ T cell (also known as killer T cells) responses to infection is the rapid initiation of a proliferative response...
Supervisor: Professor Stephen Turner
Proteins containing a PHIST (Plasmodium helical interspersed sub-telomeric) domain constitute a multi- member family that are present in the most...
Supervisor: Professor Brian Cooke
The mechanisms by which Babesia bovis causes severe disease in susceptible cattle are not well understood, however, it is clear that alterations to...
Supervisor: Professor Brian Cooke
Acinetobacter baumannii has been identified as one of the top three dangerous Gram-negative hospital pathogens as it can cause a range of life-...
Supervisor: Assoc Professor John Boyce
Characterising novel virulence mechanisms in the emerging hospital-acquired pathogen;
Acinetobacter baumannii
(A/Professor John Boyce, Dr Faye...
Supervisor: Assoc Professor John Boyce
The World Mosquito Program (WMP; based at Monash University) has pioneered a novel biocontrol tool, Wolbachia, that controls the transmission of...
Supervisor: Dr. Johanna Fraser
Pasteurella multocida is a Gram-negative bacterial pathogen that causes a number of different diseases in cattle,
pigs and poultry, resulting in...
Supervisor: Assoc Professor John Boyce
The functions of at least half of the proteins encoded in the genome of Plasmodium falciparum malaria parasites remain unknown. Understanding protein...
Supervisor: Professor Brian Cooke
Polysaccharide capsule is a critical virulence factor in many bacteria, including the priority drug-resistant pathogen Acinetobacter baumannii. The...
Supervisor: Dr Francesca Short
The gastric carcinogenic bacterium Helicobacter pylori has a unique ability to withstand high acidity of the stomach by buffering its periplasm at pH...
Supervisor: Assoc Professor Anna Roujeinikova
Exosomes are small vesicles (50-150 nm in size) secreted by most cell types and are involved in cell - cell communication and regulation of immune...
Supervisor: Professor Brian Cooke
The treatment of bacterial infections in humans and animals has largely relied on the use of antibiotics for over 70 years. One consequence of the...
Supervisor: Professor Dena Lyras
Shortly following invasion, Babesia bovis induces the formation of unique structures on the RBC surface, which we have termed ‘ridges’. Importantly,...
Supervisor: Professor Brian Cooke
Infection triggers large-scale changes in the phenotype and function of killer T cells that are critical for immune function, yet the gene regulatory...
Supervisor: Professor Stephen Turner
This project will structurally and functionally characterise the S-Pumps found in Clostridioides difficile, Bacillus solimangrovi, and Paenibacillus...
Supervisor: Dr Christopher Stubenrauch
Many bacteria are motile. Chemotaxis, mediated by chemoreceptors, plays an important role in bacterial survival and virulence. In this project, we...
Supervisor: Assoc Professor Anna Roujeinikova