Research Projects
The mRNA therapeutics have emerged as a high potent new class of drug, revolutionizing disease treatments, such as therapeutic vaccines, monoclonal...
Supervisor: Nanoantibiotics - SHEN LAB
Antibiotic-resistance is a major problem in hospitals and different community settings. Dendritic cells are sentinel cells of the innate immune...
Supervisor: Assoc Professor Meredith O'Keeffe
Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...
Supervisor: Assoc Professor Max Cryle
Type 2 diabetes (T2D) is highly prevalent, with an estimated 370 million affected individuals worldwide, and this is predicted to double by 2030....
Supervisor: Professor Colby Zaph
We have recently discovered a very potent antibody targeting the chemokine receptor CXCR3, a promising target for the treatment of inflammatory and...
Supervisor: Dr Remy Robert
The project aims to develop and deploy to the scientific community a robust method to target and isolate discrete regions within a frozen biological...
Supervisor: Assoc Professor Alex De Marco
Adaptive optics (AO) are used to improve the performance of optical systems. Through the use of AO, it is possible to compensate for any distortion...
Supervisor: Assoc Professor Alex De Marco
Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, metabolic diseases, and cancer. Namely,...
Supervisor: Dr Wael Awad
The identification of classical brown and beige adipocytes in white fat depots in adults humans has heralded a new era in adipose tissue biology with...
Supervisor: Dr Garron Dodd
Chronic infectious diseases have a devastating effect on global health. HIV and Plasmodium falciparum both cause chronic disease and have evaded...
Supervisor: Professor Kim Good-Jacobson
Circadian clocks generate daily rhythms to enhance the fitness of virtually all living organisms. Disruption of these rhythms has been implicated in...
Supervisor: Associate Professor Andrew Ellisdon
RESEARCH PROJECT BACKGROUND:
The endocrine system controls cell-cell communication and coordinates almost all our daily activities. Abnormalities in...
Supervisor: Assoc Professor Timothy Cole
Vaccines exploit the ability of the immune system to provide heightened, tailored responses to pathogens if the host has been infected prior – this...
Supervisor: Professor Kim Good-Jacobson
We wish to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co‐factor...
Supervisor: Assoc Professor Chen Davidovich
We are interested in delineating the molecular pathways that control immune cell function during infection and inflammation. Our group is focused on...
Supervisor: Professor Colby Zaph
Preliminary data from the Nguyen-Daly lab has identified Fibroblast growth factor receptors (FGFRs) as promising therapeutic targets for triple-...
Supervisor: Dr Lan Nguyen
Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, metabolic diseases, and cancer. Namely,...
Supervisor: Dr Wael Awad
In several cancer types, a higher tumour mutational burden (TMB) has been associated with increased immune cell infiltration into tumours and better...
Supervisor: Professor Nicholas Huntington
The discovery of giant viruses, comparable in size and complexity to simple cellular organisms has pushed back the frontier of the virus world....
Supervisor: Assoc Professor Fasseli Coulibaly
The Hippo/YAP signalling pathway is frequently dysregulated (~80%) in breast cancer. Yet, efforts aimed at targeting this pathway for therapeutic...
Supervisor: Dr Lan Nguyen