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Research Projects

Understanding the role of T cell cross-reactivity in human disease
Throughout life exposure to a vast array of pathogens shapes our immune system to establish a repertoire of specific memory T cells that can be...
Supervisor: Dr Nicole Mifsud
Understanding the role of the circadian molecular clock in the development of dilated cardiac myopathy and atrial fibrillation.
Virtually all cardiac functions, including the incidence of atrial fibrillation (AF) follow a circadian rhythm. Loss of appropriate timing keeping...
Supervisor: Dr Morag Young
Understanding the role of the mineralocorticoid receptor (MR) for regulating the PI3K pathway in female and male hearts.
Class IA PI3Ks are activated by receptor tyrosine kinase receptors and are critical regulators of adaptive heart growth and cardiac protection under...
Supervisor: Dr Morag Young
Urinary oxygen tension: a new biomarker of risk of acute kidney injury?
Acute kidney injury can occur in multiple hospital settings, including after major surgery (particularly when cardiopulmonary bypass is required),...
Supervisor: Professor Roger Evans
Vestibular neuromodulation in psychiatric and neurological conditions
Caloric vestibular stimulation (CVS) is a simple, safe, inexpensive bedside neuromodulation technique that has been shown to induce a wide range of...
Supervisor: Dr Steven Miller
Watching the Hippo pathway in real time in growing organs
A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have...
Supervisor: Professor Kieran Harvey
What is the role of the mineralocorticoid receptor in diabetic cardiac myopathy?
Patients with diabetes are disproportionally affected by the incidence of cardiovascular disease (CVD); diabetic cardiac myopathy (DCM) affects ~20-...
Supervisor: Dr Morag Young

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