Research Projects
HIV maturation is a highly regulated process, and viral protease has to cleave precursor of the main structural protein Gag in a sequential manner....
Supervisor: Assoc Professor Alex De Marco
Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...
Supervisor: Assoc Professor Max Cryle
FIKK kinases are unique among apicomplexan parasites. Interestingly the genome of P. falciparum encodes 20 FIKK kinases, but very little is known...
Supervisor: Professor Brian Cooke
Clostridium difficile is recognised as the major cause of nosocomial diarrhoea in Australian hospitals and in hospitals worldwide. Chronic colitis...
Supervisor: Professor Dena Lyras
Background:
Polycystic kidney disease (PKD) is the most common potentially lethal Mendelian disease, affecting around 1/1000 people. It arises when...
Supervisor: Assoc Professor Ian Smyth
Antibiotics are a precious and diminishing resource. There is a desperate need to reduce or replace the use of antibiotics to treat bacterial...
Supervisor: Professor Dena Lyras
One of the major areas of interest in our laboratory is the importance of chemokines and their receptors in the regulation of immune responses and...
Supervisor: Dr Remy Robert
Throughout life exposure to a vast array of pathogens shapes our immune system to establish a repertoire of specific memory T cells that can be...
Supervisor: Dr Nicole Mifsud
Virtually all cardiac functions, including the incidence of atrial fibrillation (AF) follow a circadian rhythm. Loss of appropriate timing keeping...
Supervisor: Assoc Prof Morag Young
Class IA PI3Ks are activated by receptor tyrosine kinase receptors and are critical regulators of adaptive heart growth and cardiac protection under...
Supervisor: Assoc Prof Morag Young
Prostate cancer is a global health challenge. Many patients with prostate cancer have positive outcomes, but some patients develop aggressive tumours...
Supervisor: Dr Mitchell Lawrence
Caloric vestibular stimulation (CVS) is a simple, safe, inexpensive bedside neuromodulation technique that has been shown to induce a wide range of...
Supervisor: Dr Steven Miller
A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have...
Supervisor: Professor Kieran Harvey
Patients with diabetes are disproportionally affected by the incidence of cardiovascular
disease (CVD); diabetic cardiac myopathy (DCM) affects ~20-...
Supervisor: Assoc Prof Morag Young