You are here

Research Projects

HIV maturation is a highly regulated process, and viral protease has to cleave precursor of the main structural protein Gag in a sequential manner....

Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...

FIKK kinases are unique among apicomplexan parasites. Interestingly the genome of P. falciparum encodes 20 FIKK kinases, but very little is known...
Supervisor: Professor Brian Cooke

Clostridium difficile is recognised as the major cause of nosocomial diarrhoea in Australian hospitals and in hospitals worldwide. Chronic colitis...
Supervisor: Professor Dena Lyras

Background: Polycystic kidney disease (PKD) is the most common potentially lethal Mendelian disease, affecting around 1/1000 people. It arises when...

Antibiotics are a precious and diminishing resource. There is a desperate need to reduce or replace the use of antibiotics to treat bacterial...
Supervisor: Professor Dena Lyras

One of the major areas of interest in our laboratory is the importance of chemokines and their receptors in the regulation of immune responses and...
Supervisor: Dr Remy Robert

Throughout life exposure to a vast array of pathogens shapes our immune system to establish a repertoire of specific memory T cells that can be...
Supervisor: Dr Nicole Mifsud

Virtually all cardiac functions, including the incidence of atrial fibrillation (AF) follow a circadian rhythm. Loss of appropriate timing keeping...

Class IA PI3Ks are activated by receptor tyrosine kinase receptors and are critical regulators of adaptive heart growth and cardiac protection under...

Prostate cancer is a global health challenge. Many patients with prostate cancer have positive outcomes, but some patients develop aggressive tumours...
Supervisor: Dr Mitchell Lawrence

Caloric vestibular stimulation (CVS) is a simple, safe, inexpensive bedside neuromodulation technique that has been shown to induce a wide range of...
Supervisor: Dr Steven Miller

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have...

Patients with diabetes are disproportionally affected by the incidence of cardiovascular disease (CVD); diabetic cardiac myopathy (DCM) affects ~20-...

Pages