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Research Projects

Studies in the Ryan lab involve understanding how protein complexes are built and how mutations in proteins cause defects in assembly. Our models are...
Supervisor: Professor Mike Ryan

A cardinal feature of adaptive CD8+ T cell (also known as killer T cells) responses to infection is the rapid initiation of a proliferative response...

This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray...

Bacteria secrete vesicles that traffic toxins to mitochondria of macrophages. This project will investigate how vesicle-delivered toxins kill...
Supervisor: Dr Thomas Naderer

The neural pathways that mediate appetite control many other functions, including mood, motivation, memory, attention and arousal, suppression of...
Supervisor: Dr Sarah Lockie

Binocular rivalry refers to the perceptual alternation that occurs every few seconds when conflicting visual stimuli are presented, one to each eye....
Supervisor: Dr Steven Miller

Single-cell analyses are at the leading edge of technological development for cell biology. And, transcriptomics analyses at single-cell resolution...

Background: Cell-based therapeutics have made advances in recent years. One of the most clinically studied products in regenerative medicine is...

Obesity is an enormous health concern, both in Australia and worldwide. Our laboratory recently published a function for the ETS-5 transcription...

Organic bioelectronics studies the development of devices that translate an electrical signal into a physiological response from cells, tissues or...
Supervisor: Dr Mark Del Borgo

Anorexia nervosa (AN) is characterised by extreme self-control, partly generated by exaggerated prefrontal cortex activity, which leads to inflexible...
Supervisor: Dr Claire Foldi

Transitive inference is a fundamental cognitive function and the basis of deductive reasoning that allows one to derive a relation between objects/...
Supervisor: Dr Mehdi Adibi

Central neural circuits subserving nutrient–activated thermogenesis - the basis of post prandial energy expenditure The ability to treat overweight...

Proteins containing a PHIST (Plasmodium helical interspersed sub-telomeric) domain constitute a multi- member family that are present in the most...
Supervisor: Professor Brian Cooke

The mechanisms by which Babesia bovis causes severe disease in susceptible cattle are not well understood, however, it is clear that alterations to...
Supervisor: Professor Brian Cooke

Acinetobacter baumannii has been identified as one of the top three dangerous Gram-negative hospital pathogens as it can cause a range of life-...

Our research program is focused on fibroblast-like stromal cells found in secondary lymphoid organs and tumours. These cells create the structure on...
Supervisor: Dr Anne Fletcher

This project will investigate the machinery involved in mitochondrial fission and fusion and the relationship between mitochondrial dynamics and...
Supervisor: Professor Mike Ryan

Background: Our group is involved in an Australia-wide program (www.kidgen.org.au) which aims to identify novel causative genes in patients with...

Characterising novel virulence mechanisms in the emerging hospital-acquired pathogen; Acinetobacter baumannii (A/Professor John Boyce, Dr Faye...

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