Research Projects
Modelling key B cell populations with age to uncover the mechanisms of autoimmunity.
Supervisor: Prasanti Kotagiri
COVID-19 vaccines are highly effective at preventing infection and severe disease from SARS-CoV-2. Although vaccination elicits neutralising...
Supervisor: Dr Paul Gill
Urinary tract infections are a common cause of bacterial infection, especially in females. These infections are often chronic or recurrent and can...
Supervisor: Dr Malcolm Starkey
Kidney stones are a common urinary tract problem. They can cause obstructions in the urinary system and are a significant risk factor for the...
Supervisor: Dr Malcolm Starkey
Plasma cells produce antibodies so are important for protection from infections. We are interested in understanding the programming of their...
Supervisor: Dr Marcus Robinson
In 1 out of 2000 people, an infection with the bacteria Streptococcus pyogenes (Strep A) can lead to acute rheumatic fever (ARF), an autoimmune...
Supervisor: Dr Danika Hill
Enduring antibody-mediated immunity is critical for vaccines to provide protection from infectious disease. Despite the success of vaccines to date,...
Supervisor: Dr Danika Hill
Plasma cells (PC) are the only cell type secreting antibodies, which are important for protective immunity to fight against pathogens. However,...
Supervisor: Dr Zhoujie (Zoe) Ding
Chronic immune-related comorbidities such as autoimmunity, bronchiectasis (irreversible lung damage), and gastrointestinal disease affect up to 68%...
Supervisor: Dr Emily Edwards
Profiling auto-reactive B cells and their targets with the goal to identify shared antigenic responses.
Supervisor: Prasanti Kotagiri
From early in life we are exposed to trillions of microbes and food proteins through our intestines, and only occassionally are the microbes...
Supervisor: Dr Marcus Robinson
The primary means of protective immunity coming from vaccines is the formation of long-lived, antibody-producing plasma cells. However, not all...
Supervisor: Dr Marcus Robinson
Type 2 immune bias is associated with the final stages of lung development and we have recently shown that eosinophils play a key role in this...
Supervisor: Assoc Professor Margaret Hibbs
Long COVID has emerged as a global health issue with long-term social and economic impacts. It is estimated that 5-10% of people infected with SARS-...
Supervisor: Dr Paul Gill
Development of protein nanopores for long sequence genome reading
Supervisor: Assoc Professor Michelle Dunstone
Group A Streptococcus (GAS) is typically associated with relatively mild skin or throat infections but may also progress to extremely dangerous...
Supervisor: Dr Danika Hill
Stroke is a leading cause of mortality and morbidity. Bacterial infections are one of the most common complications following stroke. Bacterial...
Supervisor: Dr Malcolm Starkey
Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...
Supervisor: Assoc Professor Margaret Hibbs
Characterising donor specific B cells and how this relates to transplantation outcomes.
Supervisor: Prasanti Kotagiri
The bladder is a unique and often forgotten mucosal site. When the bladder is exposed to bacterial pathogens it sheds superficial epithelial cells to...
Supervisor: Dr Malcolm Starkey