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Research Projects

Modelling key B cell populations with age to uncover the mechanisms of autoimmunity.
Supervisor: Prasanti Kotagiri

COVID-19 vaccines are highly effective at preventing infection and severe disease from SARS-CoV-2. Although vaccination elicits neutralising...
Supervisor: Dr Paul Gill

Urinary tract infections are a common cause of bacterial infection, especially in females. These infections are often chronic or recurrent and can...
Supervisor: Dr Malcolm Starkey

Kidney stones are a common urinary tract problem. They can cause obstructions in the urinary system and are a significant risk factor for the...
Supervisor: Dr Malcolm Starkey

Plasma cells produce antibodies so are important for protection from infections. We are interested in understanding the programming of their...
Supervisor: Dr Marcus Robinson

In 1 out of 2000 people, an infection with the bacteria Streptococcus pyogenes (Strep A) can lead to acute rheumatic fever (ARF), an autoimmune...
Supervisor: Dr Danika Hill

Enduring antibody-mediated immunity is critical for vaccines to provide protection from infectious disease. Despite the success of vaccines to date,...
Supervisor: Dr Danika Hill

Plasma cells (PC) are the only cell type secreting antibodies, which are important for protective immunity to fight against pathogens. However,...
Supervisor: Dr Zhoujie (Zoe) Ding

Chronic immune-related comorbidities such as autoimmunity, bronchiectasis (irreversible lung damage), and gastrointestinal disease affect up to 68%...
Supervisor: Dr Emily Edwards

Profiling auto-reactive B cells and their targets with the goal to identify shared antigenic responses.
Supervisor: Prasanti Kotagiri

From early in life we are exposed to trillions of microbes and food proteins through our intestines, and only occassionally are the microbes...
Supervisor: Dr Marcus Robinson

The primary means of protective immunity coming from vaccines is the formation of long-lived, antibody-producing plasma cells. However, not all...
Supervisor: Dr Marcus Robinson

Type 2 immune bias is associated with the final stages of lung development and we have recently shown that eosinophils play a key role in this...

Long COVID has emerged as a global health issue with long-term social and economic impacts. It is estimated that 5-10% of people infected with SARS-...
Supervisor: Dr Paul Gill

The discovery of innate lymphoid cells (ILCs) has revealed their central role in maintaining intestinal homeostasis and protecting against...

Development of protein nanopores for long sequence genome reading

Group A Streptococcus (GAS) is typically associated with relatively mild skin or throat infections but may also progress to extremely dangerous...
Supervisor: Dr Danika Hill

Stroke is a leading cause of mortality and morbidity. Bacterial infections are one of the most common complications following stroke. Bacterial...
Supervisor: Dr Malcolm Starkey

Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...

There is accumulating evidence that diet can play a key role in improving depressive symptoms. The most compelling evidence so far is for traditional...

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