Description
Chronic immune-related comorbidities such as autoimmunity, bronchiectasis (irreversible lung damage), and gastrointestinal disease affect up to 68% of patients with Inborn Errors of Immunity (IEI). These conditions often mask the underlying diagnosis of IEI, leading to diagnostic delays of up to 9 years and causing lasting organ damage, reduced quality of life and life expectancy. Using analysing patient samples, this project aims to identify biomarkers to improve early detection, monitor disease progression, and guide new treatment strategies.
Students will learn to isolate PBMCs, perform immune profiling and functional immune assays, culture, analyse multicolour spectral flow cytometry data using FlowJo and clinical data to identify biomarkers of disease.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
immunodeficiency, immune profiling, immune signalling, genetics, immune system function
School
School of Translational Medicine » Immunology and Pathology
Available options
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Joint PhD/Exchange Program
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Alfred
Research webpage
Co-supervisors
Dr
Julian Bosco