Research Projects
The eukaryotic genome consists of two classes of genes preceded by distinctly different promoter sequences. Housekeeping genes (90%) code for...
Supervisor: Dr Dominika Elmlund
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
A major challenge in cancer therapeutics is to kill tumour cells without harming normal cells in the body. Traditional chemotherapy tries to do this...
Supervisor: Dr Lan Nguyen
Helicobacter pylori persistently colonize the epithelium of the stomach in roughly half of the world’s population. It is a causative agent of...
Supervisor: Assoc Professor Anna Roujeinikova
Cancer therapy and oncology has entered a new exciting era of targeted therapy and personalised patient treatment, but resistance and tumour...
Supervisor: Dr Lan Nguyen
In recent years, the landscape of cancer therapy has shifted dramatically. Novel approaches based on harnessing the patient’s own immune system have...
Supervisor: MICHAEL CHOPIN, PHD
Helicobacter pylori is a pathogenic bacterium that infects the stomachs of half the world's population, causing chronic gastritis, ulcers, and...
Supervisor: Assoc Professor Anna Roujeinikova
The project: Antigen presenting cells (APCs) play a crucial role in establishing and maintaining an immune response towards cancer cells. In recent...
Supervisor: Professor Anthony Purcell
Psoriasis is a skin autoimmune disease that affects 2-3% of the global population. Around half of the patients carry the major risk gene for...
Supervisor: Dr. Asolina Braun
This project investigates the novel architecture of the power system found in a bacterial flagellar motor specialised for locomotion in viscous...
Supervisor: Assoc Professor Anna Roujeinikova
Studies in the Ryan lab involve understanding how protein complexes are built and how mutations in proteins cause defects in assembly. Our models are...
Supervisor: Professor Mike Ryan
This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and
cell membranes through x-ray...
Supervisor: Professor Mibel Aguilar
Bacteria secrete vesicles that traffic toxins to mitochondria of macrophages. This project will investigate how vesicle-delivered toxins kill...
Supervisor: Dr Thomas Naderer
RNA sequencing technologies enable the simultaneous detection of tens of thousands of genes, providing researchers with a powerful tool for...
Supervisor: Professor Wei Shi
Single-cell analyses are at the leading edge of technological development for cell biology. And, transcriptomics analyses at single-cell resolution...
Supervisor: A/Prof Traude Beilharz
Our research program is focused on fibroblast-like stromal cells found in secondary lymphoid organs and tumours. These cells create the structure on...
Supervisor: Dr Anne Fletcher
This project will investigate the machinery involved in mitochondrial fission and fusion and the relationship between mitochondrial dynamics and...
Supervisor: Professor Mike Ryan
It is now well-established that the cancer stroma, including cancer-associated fibroblasts, plays a major role in development and progression of this...
Supervisor: Professor Roger Daly
Given their natural adjuvant properties, and their unique attributes in promoting T cell priming and recruitment into solid tumors, dendritic cells (...
Supervisor: MICHAEL CHOPIN, PHD
Langerhans cells are specialized dendritic cells localized in the skin, and exclusively express CD1a on the cell surface. CD1a presents lipids found...
Supervisor: Dr Adam Shahine