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Research Projects

Frontotemporal dementia (FTD) is generally due to abnormalities either in a protein called tau (45%) or a protein called TDP-43 (45%). In both types...

Epilepsy is a serious neurological condition which is characterised by spontaneous seizures, or 'fits'. Current medications are effective...

Surgery is the most effective treatment for stopping seizures in epilpesy. But which patients will benefit from surgery, and how to best perform the...
Supervisor: Dr Ben Sinclair

The glymphatic system is the brain's method for clearing waste products to allow for appropriate functioning. In certain diseases, this system...

This is a qualitative study looking at how children's lives are impacted by having a parent with functional seizures.
Supervisor: Dr Lana Higson

Epilepsy is complex brain disorder, and many patients are not adequately treated with existing therapies. New therapeutic avenues are needed, such as...

Post-traumatic epilepsy (PTE) accounts for 20% of symptomatic epilepsy. Despite multiple studies have identified male sex as one of the risk factors...
Supervisor: Dr. Runxuan Lin

Brain inflammation appears to play a critical role in the pathogenesis of epilepsy. A major cell type involved in inflammatory cascades are the...

Most neurological disorders, e.g. Alzheimer's, Parkinson's Disease, etc.. are associated with the build up of toxic proteins, which can...
Supervisor: Dr Ben Sinclair

There is no defined optimal treatment for functional cognitive disorders (FCD), despite effective treatments being desperately needed. This research...
Supervisor: Dr Lana Higson

Epilepsy is one of the most common serious chronic neurological disorders and is estimated to affect approximately 68 million people worldwide....

Paediatric chronic pain is defined by the International Association for the Study of Pain as persistent or recurring pain that lasts for longer than...

Declining cognitive function is common in multiple sclerosis (MS) and routine cognitive testing is critically needed in MS care. However,...
Supervisor: Dr Daniel Merlo

This project is at the intersection of neuroscience, data science and artificial intelligence. Coordinated brain activity underpins all cognitive...

The development of reliable, accurate, non-invasive methodologies for continuous, long-term seizure monitoring is a critical part of the precision...

Clinical trial frameworks and funders agree on the importance of engaging with consumers and the community within the health and medical research...

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