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Stimulating the brain to treat epilepsy

Description 
Epilepsy is a serious neurological condition which is characterised by spontaneous seizures, or 'fits'. Current medications are effective in about 70% of patients, but can have important side effects. New therapies are desperately needed to address this treatment gap. Here we will use animal models to test a new therapy for epilepsy involving a novel type of brain stimulation. This is non-invasive, simple, and readily translatable to the clinic. Stimulating the brain at a specific frequency increases brain rhythms, which in turn can affect brain neurochemistry and neuroinflammation. These attributes may well be able to influence seizure susceptibility. Techniques which will be learnt include animal modelling of epilepsy, surgery, in vivo electrophysiology, epilepsy monitoring, development refinement of the stimulation paradigm, post-mortem measures of neuroinflammation, molecular biology
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
epilepsy, mouse model, seizures, neuroinflammation, brain stimulation,
School 
Central Clinical School » Neuroscience
Available options 
PhD/Doctorate
Masters by research
Masters by coursework
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Alfred Research Alliance
Co-supervisors 
Dr 
Matt Hudson
Dr 
Idrish Ali
Dr 
Juliana Silva

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