Research Projects
Despite enormous progress in research, cancer remains a devastating disease worldwide. Since generally not all patients will respond to a specific...
Supervisor: Dr Lan Nguyen
A blow to the head causes a number of behavioural, cognitive, emotional, sensory and motor problems. We are interested in the brain changes that...
Supervisor: Professor Ramesh Rajan
Anorexia Nervosa (AN) has a mortality rate 12 times higher than the annual death rate from all causes in females aged 15 to 24. Currently, there is...
Supervisor: Professor Brian Oldfield
Cancer cachexia is the progressive loss of body weight, accompanied by loss of appetite, which affects around 80% of cancer patients. Inappropriate...
Supervisor: Dr Sarah Lockie
We are constantly bombarded with sensory information, and our brains need a mechanism to filter out necessary information. The process of visual...
Supervisor: Dr Maureen Hagan
Damage to primary visual cortex will cause cortical blindness, a condition where patients no longer have conscious visual perception in the parts of...
Supervisor: Dr Leo Lui
The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...
Supervisor: Assoc Professor Jose Polo
Tuberous sclerosis, or “tuberous sclerosis complex” (TSC), is a lifelong genetic disorder that affects millions of individuals. TSC is manifest in...
Supervisor: Dr Charles Bayly-Jones
Industry-Academia PhD Position
New tools for immunopeptidomics
An opportunity for an outstanding PhD candidate to undertake a collaborative...
Supervisor: Professor Anthony Purcell
Therapies that enhance the immune response to tumours have revolutionised the management of cancer. However, most tumours do not have a high...
Supervisor: Professor Tony Tiganis
Background: Mitochondria are energy-producing organelles. They form a network inside cells, and their health is critical to cell function....
Supervisor: Dr Georg Ramm
Natural killer (NK) cells are innate lymphocytes that play a vital role in the immune response through their ability to directly kill transformed and...
Supervisor: Professor Nicholas Huntington
The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of...
Supervisor: Professor Nicholas Huntington
Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, cancer, and metabolic diseases. Initially,...
Supervisor: Dr Wael Awad
Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly
Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose
One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...
Supervisor: Professor Mibel Aguilar
Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott
Primary liver cancer is one of the world’s deadliest cancers and the third most common cause of cancer death. Hepatocellular carcinoma (HCC)...
Supervisor: Professor Tony Tiganis
Cubosomes have attracted widespread attention in the pharmaceutical industry due to their high stability, ability to contain amphiphilic drugs,...
Supervisor: Nanoantibiotics - SHEN LAB