Research Projects
Obesity and overweight are major health concerns and a burden to public health in Australia, affecting 2 in 3 adults (12.5 million), and 1 in 4...
Supervisor: Professor Zane Andrews
We have identified specific sphingolipids that control brain development and protect the nervous system throughout life. This exciting project will...
Supervisor: Professor Roger Pocock
The Combes laboratory has opportunities for postgraduate research projects in animal and stem cell models of kidney development and disease, advanced...
Supervisor: Dr Alex Combes
Perforin and the Complement Membrane Attack Complex (MAC) are related pore forming immune effectors that are deployed by the immune system to...
Supervisor: Professor James Whisstock
In this project, in collaboration with Professor Ross Hannan (ANU), we will study the structure of Upstream Binding Factor (UBF) in complex with...
Supervisor: Professor James Whisstock
Nanocomposite biomaterials are an emerging area of research as we seek to optimise the properties of biomaterials to enhance their suitability for...
Supervisor: Dr Mark Del Borgo
Like many developed countries, the population of Australia is ageing; with 13.8% of the population currently over the age of 65 and predictions this...
Supervisor: Professor Nicole La Gruta
Cancer cachexia is a life-threatening condition characterised by a progressive loss of skeletal muscle and fat mass. Up to 80% of patients with...
Supervisor: Assoc Professor Craig Harrison
Atherosclerosis, the process by which fats, cholesterol and other substances build up in the artery wall, is the leading cause of CV disease. This...
Supervisor: Dr Kristen Bubb
The global threat from antimicrobial resistance (AMR) was highlighted by the World Health Organization in its first-ever priority pathogen list of...
Supervisor: Dr Meiling Han
This project aims to develop novel antisense oligonucleotides as an efficient and common therapeutic for targeting the polymyxin resistant gram-...
Supervisor: Dr Nitin Patil
The transcript encoding the proto-oncogene MYC is commonly overexpressed in prostate cancer (PC). MYC protein abundance is also increased in the...
Supervisor: Dr Luc Furic
Hypertension is a major cause of heart failure, heart attacks and strokes. Associated with the development of hypertension is the accumulation of...
Supervisor: Dr Barbara Kemp-Harper
Pulmonary hypertension (PH) is an incurable disease and a major cause of death and illness throughout the world. Whilst there has been advancement...
Supervisor: Dr Barbara Kemp-Harper
Background:
Strong climatic changes may have been the primary drivers of human evolution. Understanding how early human (hominin) foraging and...
Supervisor: A/Prof Luca Fiorenza
The mineralocorticoid receptor (MR) is a ligand activated transcription factor that is important for physiological control of blood pressure and...
Supervisor: Professor Morag J. Young
Obesity is a major public health burden worldwide, where 2/3 Australians are overweight and/or obese. Obesity greatly increases the risk of diabetes...
Supervisor: Dr Denuja Karunakaran
DC monitor the environment for potential “danger signals” that signify pathogen invasion, including non-homeostatic cell death caused by viruses. We...
Supervisor: Assoc Professor Mireille Lahoud
Thin, flat, branched actin cytoskeleton filled membrane protrusions like the lamellipodia and membrane ruffles are utilized by cells for a plethora...
Supervisor: Dr Senthil Arumugam
The presentation of post-translationally modified (PTM) peptides by cell surface MHC molecules increases the diversity of targets for recognition by...
Supervisor: Dr Nathan Croft