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NK Cell - Single Cell Transcriptomics

Description 
Natural killer (NK) cells are innate lymphocytes that play a vital role in the immune response through their ability to directly kill transformed and virus infected cells, and by orchestrating the early phase of the adaptive immune response. This project will utilise single-cell RNA sequencing resources to decipher the regulation of genes involved in lysosomal biogenesis. The results may identify important gene programs driving functional diversification and specialization during NK cell differentiation and hold potential to guide new strategies for NK cell-based cancer immunotherapy.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
NK cell; transcription factors
Available options 
PhD/Doctorate
Masters by research
Honours
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
No
Physical location 
15 Innovation Walk
Co-supervisors 
Dr 
Aline Pfefferle

Want to apply for this project? Submit an Expression of Interest by clicking on Contact the researcher.