Research Projects
Studies from lower order organisms such as flies and worms have shown that mild mitochondrial dysfunction invokes a stress response that promotes...
Supervisor: Dr Adam Rose
RESEARCH BACKGROUND
Parkinson’s disease (PD) is one of the most common of the neurodegenerative disorders, affecting 1-2% of the population...
Supervisor: Dr Michael Lazarou
Eating disorders and drug addiction share many common traits, including biological and environmental factors that predispose individuals to...
Supervisor: Dr Claire Foldi
The epidemic of chronic kidney disease (CKD) and end-stage renal failure represents a crisis for health world-wide. Recent work indicates that CKD...
Supervisor: Professor Sharon Ricardo
Metallo‐peptidases cleave amino acids from either the N‐ and C‐termini of peptide hormones to either generate or degrade biologically active peptides...
Supervisor: Assoc Professor Siew Yeen Chai
Fibroblasts in the lymph nodes are able to regulate differentiation and localization of innate and adaptive immune cells. They are also a primary...
Supervisor: Dr Kostas Knoblich
TCR recognition of peptide + MHC class I complexes (pMHCI) is central to CD8+ T cell function. It is clear that the nature of the TCR-pMHCI...
Supervisor: Professor Nicole La Gruta
DC take up, process and present antigen (Ag) to T cells to initiate immune responses. There are multiple DC subsets that are tailored for different...
Supervisor: Assoc Professor Mireille Lahoud
The success of the immune system in protecting the host from a multitude of foreign pathogens is in large part due to its adaptability. The immune...
Supervisor: Dr Kim Jacobson
Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disorder - 12 times higher than the death rate from all other causes in...
Supervisor: Dr Claire Foldi
Damage to myelin, the insulating sheath surrounding nerves, is a common consequence of traumatic brain injury. Emerging evidence suggests that white...
Supervisor: Dr Bridgette Semple
A central feature of inflammatory diseases is the migration of white blood cells into the affected tissues. This is controlled by a group of proteins...
Supervisor: Assoc Professor Martin Stone
We are interested in defining the biological principles that define connectivity between cells in the primate brain. This requires information about...
Supervisor: Professor Marcello Rosa
Despite enormous progress in research, cancer remains a devastating disease worldwide. Since generally not all patients will respond to a specific...
Supervisor: Dr Lan Nguyen
A blow to the head causes a number of behavioural, cognitive, emotional, sensory and motor problems. We are interested in the brain changes that...
Supervisor: Professor Ramesh Rajan
Anorexia Nervosa (AN) has a mortality rate 12 times higher than the annual death rate from all causes in females aged 15 to 24. Currently, there is...
Supervisor: Professor Brian Oldfield
Cancer cachexia is the progressive loss of body weight, accompanied by loss of appetite, which affects around 80% of cancer patients. Inappropriate...
Supervisor: Dr Sarah Lockie
Damage to primary visual cortex will cause cortical blindness, a condition where patients no longer have conscious visual perception in the parts of...
Supervisor: Dr Leo Lui
The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...
Supervisor: Assoc Professor Jose Polo
The cochlea is the organ of the inner ear essential for hearing. It is embedded in the skull and converts sound waves into electrical impulses...
Supervisor: Professor Phillip Bird