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Research Projects

Studies from lower order organisms such as flies and worms have shown that mild mitochondrial dysfunction invokes a stress response that promotes...
Supervisor: Dr Adam Rose

RESEARCH BACKGROUND Parkinson’s disease (PD) is one of the most common of the neurodegenerative disorders, affecting 1-2% of the population...
Supervisor: Dr Michael Lazarou

Eating disorders and drug addiction share many common traits, including biological and environmental factors that predispose individuals to...
Supervisor: Dr Claire Foldi

The epidemic of chronic kidney disease (CKD) and end-stage renal failure represents a crisis for health world-wide. Recent work indicates that CKD...

Metallo‐peptidases cleave amino acids from either the N‐ and C‐termini of peptide hormones to either generate or degrade biologically active peptides...

Fibroblasts in the lymph nodes are able to regulate differentiation and localization of innate and adaptive immune cells. They are also a primary...
Supervisor: Dr Kostas Knoblich

TCR recognition of peptide + MHC class I complexes (pMHCI) is central to CD8+ T cell function. It is clear that the nature of the TCR-pMHCI...

DC take up, process and present antigen (Ag) to T cells to initiate immune responses. There are multiple DC subsets that are tailored for different...

The success of the immune system in protecting the host from a multitude of foreign pathogens is in large part due to its adaptability. The immune...
Supervisor: Dr Kim Jacobson

Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disorder - 12 times higher than the death rate from all other causes in...
Supervisor: Dr Claire Foldi

Damage to myelin, the insulating sheath surrounding nerves, is a common consequence of traumatic brain injury. Emerging evidence suggests that white...
Supervisor: Dr Bridgette Semple

A central feature of inflammatory diseases is the migration of white blood cells into the affected tissues. This is controlled by a group of proteins...

We are interested in defining the biological principles that define connectivity between cells in the primate brain. This requires information about...

Despite enormous progress in research, cancer remains a devastating disease worldwide. Since generally not all patients will respond to a specific...
Supervisor: Dr Lan Nguyen

A blow to the head causes a number of behavioural, cognitive, emotional, sensory and motor problems. We are interested in the brain changes that...

Anorexia Nervosa (AN) has a mortality rate 12 times higher than the annual death rate from all causes in females aged 15 to 24. Currently, there is...

Cancer cachexia is the progressive loss of body weight, accompanied by loss of appetite, which affects around 80% of cancer patients. Inappropriate...
Supervisor: Dr Sarah Lockie

Damage to primary visual cortex will cause cortical blindness, a condition where patients no longer have conscious visual perception in the parts of...
Supervisor: Dr Leo Lui

The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...

The cochlea is the organ of the inner ear essential for hearing. It is embedded in the skull and converts sound waves into electrical impulses...

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