Research Projects
Cancer cachexia is the progressive loss of body weight, accompanied by loss of appetite, which affects around 80% of cancer patients. Inappropriate...
Supervisor: Dr Sarah Lockie
Damage to primary visual cortex will cause cortical blindness, a condition where patients no longer have conscious visual perception in the parts of...
Supervisor: Dr Leo Lui
The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...
Supervisor: Assoc Professor Jose Polo
The cochlea is the organ of the inner ear essential for hearing. It is embedded in the skull and converts sound waves into electrical impulses...
Supervisor: Professor Phillip Bird
We are facing an era where the antibiotic cornerstone of modern medicine is under threat due to bacterial resistance. Deadly superbugs are not only...
Supervisor: Dr Jennifer Payne
Background: Mitochondria are energy-producing organelles. They form a network inside cells, and their health is critical to cell function....
Supervisor: Dr Georg Ramm
Natural killer (NK) cells are innate lymphocytes that play a vital role in the immune response through their ability to directly kill transformed and...
Supervisor: Professor Nicholas Huntington
The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of...
Supervisor: Professor Nicholas Huntington
Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly
Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose
One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...
Supervisor: Professor Mibel Aguilar
Background
Nuclear transport is central to eukaryotic cell processes such as signal transduction and differentiation, where changes in transcription...
Supervisor: Professor David Jans
Nuclear transport inhibitors to combat diseases
Two major health burdens world-wide are cancer and infectious diseases like viral illnesses and...
Supervisor: Professor David Jans
Hepatocellular carcinoma (HCC) is one of the most fatal and fastest growing cancers. In recent years, non-alcoholic steatohepatitis (NASH) has been...
Supervisor: Professor Colby Zaph
The Prostate Cancer Research Group is a group of scientists and clinical fellows working together to study male urological biology and disease....
Supervisor: Professor Gail Risbridger
This project aims to engineer new biomaterials that can permanently integrate with the brain. This project expects
to generate new knowledge using...
Supervisor: Professor Mibel Aguilar
Every ageing woman faces potentially debilitating physical symptoms following the cessation of ovarian function at menopause. Crucially, many of...
Supervisor: Dr Kelly Walton
Gonadal-derived inhibin A and inhibin B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle...
Supervisor: Assoc Professor Craig Harrison
This project aims to determine how antibiotic resistance and toxin plasmids are replicated and maintained in this important bacterial pathogen
Supervisor: Professor Julian Rood
Pleurotolysin: a pore forming toxin from the carnivorous oyster mushroom
Supervisor: Assoc Professor Michelle Dunstone