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Research Projects

Background Nuclear transport is central to eukaryotic cell processes such as signal transduction and differentiation, where changes in transcription...
Supervisor: Professor David Jans

Nuclear transport inhibitors to combat diseases Two major health burdens world-wide are cancer and infectious diseases like viral illnesses and...
Supervisor: Professor David Jans

Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott

Primary liver cancer is one of the world’s deadliest cancers and the third most common cause of cancer death. Hepatocellular carcinoma (HCC)...

Hepatocellular carcinoma (HCC) is one of the most fatal and fastest growing cancers. In recent years, non-alcoholic steatohepatitis (NASH) has been...
Supervisor: Professor Colby Zaph

Cubosomes have attracted widespread attention in the pharmaceutical industry due to their high stability, ability to contain amphiphilic drugs,...

Oligodendrocytes play a vital role as supporting cells within the central nervous system, aiding in signal transmission among a plethora of other...
Supervisor: Yasith Mathangasinghe

Advanced age is the strongest risk factor for cancer development, with 1 in 2 persons developing cancer by age 85. Despite being a strong predictor...
Supervisor: Dr Lochlan Fennell

Frequent resistance to single-agent treatment means that doctors are turning to combination therapy, i.e. ‘cocktails of drugs’, to beat resistance....
Supervisor: Dr Lan Nguyen

This project aims to engineer new biomaterials that can permanently integrate with the brain. This project expects to generate new knowledge using...

Every ageing woman faces potentially debilitating physical symptoms following the cessation of ovarian function at menopause. Crucially, many of...
Supervisor: Dr Kelly Walton

Gonadal-derived inhibin A and inhibin B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle...

This project aims to determine how antibiotic resistance and toxin plasmids are replicated and maintained in this important bacterial pathogen
Supervisor: Professor Julian Rood

Pleurotolysin: a pore forming toxin from the carnivorous oyster mushroom

Protein-RNA interactions are integral to cellular biology – both in normal cellular function and also in cells subject to the stresses of viral...

Putting the brakes on inflammation: Using the structure of important immune protein receptors to develop therapeutics

The sheer mechanical power of shark jaws, combined with an increase in shark bites in Australia since the 2000s, have accelerated the need for the...

Over the past years, our scientific and clinical research team has pursued basic discovery and preclinical research into the skin autoimmune disease...
Supervisor: Dr. Asolina Braun

Background: Factors influencing the life-histories of a species are poorly understood and little is known about how ecology modulates the pace of...
Supervisor: A/Prof Luca Fiorenza

Gamma-aminobutyric acid (GABA) produced by Glutamic Acid Descarboxylase (GAD) is the most abundant neurotransmitter inhibitor in the CNS and is...

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