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Research Projects

Many bacteria are motile. Chemotaxis, mediated by chemoreceptors, plays an important role in bacterial survival and virulence. In this project, we...

Some metabolic enzymes are upregulated in the liver of mice and humans with wasting disorders. Here we will test whether and how these enzymes impact...
Supervisor: A/Prof. Adam Rose

Recently, renal denervation (removing the renal nerves) has been shown to be an effective and safe treatment for human resistant hypertension and is...

Tumours lose features of multicellularity, such as tissue differentiation and coordinated cell division, and start to resemble colonial unicellular...
Supervisor: Dr David Goode

Cancer follows an evolutionary process shaped by the environment of the tumour. Deciphering which genes and processes enable tumour cells to adapt to...
Supervisor: Dr David Goode

Our laboratory aims to create new knowledge in host-pathogen interactions driven by intracellular bacterial pathogens. Our research team has projects...

Mapping the topography and the conditions of indoor/outdoor terrains is an important ongoing research area, as terrain mapping is required for safe...

This project uses spatial proteomics and transcriptomics data to map locations of immune cells within the vicinity of paediatric and adult brain...
Supervisor: Dr David Goode

Antibiotic resistance continues to emerge and intensify. Antimicrobial peptides (AMPs) are a promising alternative to current antibiotics, but...

The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...

Unlike other infections in which one single encounter with the pathogen is enough to induce long-lasting protection, immunity to malaria might take...
Supervisor: Prof Diana Hansen

Viruses pose one of the grand challenges to human and animal health globally and within Australia. Viral disease progression is critically dependent...
Supervisor: Dr Gregory Moseley

Neuroanatomy is a cornerstone of medical education, providing the foundational knowledge required to diagnose and treat neurological disorders. A...
Supervisor: Yasith Mathangasinghe

Stroke and trauma are the leading causes of brain damage in Australia. Although many people survive the initial event, they are left with devastating...
Supervisor: Leon Smyth

RESEARCH BACKGROUND Parkinson’s disease (PD) is one of the most common of the neurodegenerative disorders, affecting 1-2% of the population...
Supervisor: Dr Michael Lazarou

Eating disorders and drug addiction share many common traits, including biological and environmental factors that predispose individuals to...
Supervisor: Dr Claire Foldi

The human brain is wrinkled: a design thought to maximize the number of neurons packed into the limited space of the skull. But recent AI-driven...

Metallo‐peptidases cleave amino acids from either the N‐ and C‐termini of peptide hormones to either generate or degrade biologically active peptides...

Fibroblasts in the lymph nodes are able to regulate differentiation and localization of innate and adaptive immune cells. They are also a primary...
Supervisor: Dr Kostas Knoblich

TCR recognition of peptide + MHC class I complexes (pMHCI) is central to CD8+ T cell function. It is clear that the nature of the TCR-pMHCI...

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