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Research Projects

Caspases are critical mediators of programmed cell death. We recently demonstrated that they are not only involved in killing cells, but in...

Many bacterial pathogens have acquired the capacity to replicate inside human cells by avoiding cell intrinsic innate immune pathways. Pathogens such...

Many peptide hormones act inside a cell, regulating intracellular events. These peptide/protein hormones, which have intracellular functions, are...

Injuries to the nervous system can cause lifelong disabilities due to ineffective repair of the damaged nerve fibres and thus, understanding the...
Supervisor: Dr Brent Neumann

The risk of persistent Human Papillomavirus (HPV) infection, cervical dysplasia and HPV-related cancers is unknown in women with multiple sclerosis (...

Knee osteoarthritis is a major public health problem. The role of bone, integral to the pathogenesis of knee OA, is receiving increasing attention as...

*Small and large projects available Mortality, routinely collected worldwide, is recognised as one of the finest indicators of health, or ill...
Supervisor: Dr Rosanne Freak-Poli

We have discovered a new cytokine exclusively expressed in the female reproductive tract, which is essential for the optimal response to Sexually...

Novel epigenetic treatments for myelodysplastic syndrome improve survival. Epigenetic therapy (EGT) regimes are often lengthy as responses are...

Our studies aim to understand how viruses, such as rhinovirus and influenza, cause asthma attacks. Previous studies in our laboratory (Thomas et al...
Supervisor: Dr Belinda Thomas

Proteins containing a PHIST (Plasmodium helical interspersed sub-telomeric) domain constitute a multi- member family that are present in the most...
Supervisor: Professor Brian Cooke

The mechanisms by which Babesia bovis causes severe disease in susceptible cattle are not well understood, however, it is clear that alterations to...
Supervisor: Professor Brian Cooke

For the majority of DSD cases the underlying genetic aetiology is unknown. In males Sox9 is a critical ‘hub’ gene involved in sexual development. We...

Our lab is interested in immune cells within the central nervous system (CNS), and how these cells contribute to neuroinflammation and neurological...
Supervisor: Dr Samantha Dando

Acinetobacter baumannii has been identified as one of the top three dangerous Gram-negative hospital pathogens as it can cause a range of life-...

Research Aims: 1. to evaluate splenic function in patients labelled as congenital asplenics 2. to describe the clinical and immunological function...
Supervisor: Dr Ian Woolley

Our research program is focused on fibroblast-like stromal cells found in secondary lymphoid organs and tumours. These cells create the structure on...
Supervisor: Dr Anne Fletcher

This project will investigate the machinery involved in mitochondrial fission and fusion and the relationship between mitochondrial dynamics and...
Supervisor: Professor Mike Ryan

Characterisation, modelling and development of high precision cooperative multi-arm manipulation system for constrained environments [collaboration...

Approximately 55% of patients with neuromyelitis optica spectrum disorder show cognitive impairment as evaluated using the Rao Brief Repeatable...

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