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Research Projects

The Y-chromosome gene, SRY, is widely expressed in the male brain, such as the substantia nigra, ventral tegmental area (VTA), pre-frontal cortex (...
Supervisor: Dr Joohyung Lee

Pelvic organ Prolapse (POP) is a debilitating urogynecological disorder arising from vaginal birth trauma that goes unrecognised, and culminates as a...
Supervisor: Dr Shayanti Mukherjee

Lung cancer patient's die from metastatic disease, not primary disease. In the case of small cell lung cancer the brain is a primary site of...
Supervisor: A/Prof Daniel Gough

Osteosarcoma is the most prevalent primary bone tumour, with a predominance in children and adolescents in periods of rapid growth. Despite...
Supervisor: A/Prof Jason Cain

Epigenetics provides an interface between the environment and DNA function through the ability of epigenetic modifications to regulate gene...

Pattern recognition receptors, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), are key components of the innate immune response....

Osteosarcoma is the most prevalent primary malignant tumour of the bone, mainly affecting teenagers and young adults, particularly during growth...
Supervisor: A/Prof Jason Cain

Our laboratory has for the first time identified a new NOD-like receptor (NLR) protein in the regulation of inflammation in response to chronic...

Genome-wide association studies (GWAS) have been instrumental in discovering these loci, and they have successfully identified numerous disease-...
Supervisor: Dr Sathish Periyasamy

There are over 7,000 rare diseases that on average take ~4 years to diagnose, during which families consult on average 5 doctors and receive 3...

There is a well defined difference between a novice and an expert in surgical training and simulation-based educational programmes and research....

Determination of intermediate surgical skill in surgeons, a simulation-based educational validation study

Clinical trials have been criticized for not having gender balance. However, there is a lack of understanding of the reasons why this may have...
Supervisor: Professor Thanh Phan

We are developing 3-dimensional human brain organoids using induced pluripotent stem cells (iPSCs). We can model the effect of neuroinflammation in...
Supervisor: Dr Courtney McDonald

The COVID-19 outbreak, caused by the SARS-CoV-2 virus, has shown high infection and mortality rates worldwide. Although most people experience mild...
Supervisor: Dr Joohyung Lee

Spectroscopy, an analytical chemical technique is an attractive approach for analysing human disease for biomarker discovery. Biospecimens can be...
Supervisor: Dr Charlotte Keung

Inflammation-induced brain injury remains one of the main causes of lifelong disability after birth. There is no effective treatment. Elevated levels...
Supervisor: Dr Robert Galinsky

Exposure to infection/inflammation during the perinatal period is one of the main causes of impaired neurodevelopment. To develop effective...
Supervisor: Dr Robert Galinsky

Photodynamic therapy (PDT) is an established treatment for cancer which relies on the use of a specific wavelength of light to activate a compound (...
Supervisor: Dr Daniel Garama

Development and evaluation of a national paediatric surgery simulation-based education programme for consent

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