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Research Projects

We are facing an era where the antibiotic cornerstone of modern medicine is under threat due to bacterial resistance. Deadly superbugs are not only...
Supervisor: Dr Jennifer Payne

Tuberous sclerosis, or “tuberous sclerosis complex” (TSC), is a lifelong genetic disorder that affects millions of individuals. TSC is manifest in...

Pneumonia is highly prevalent and often deadly in stroke patients, raising the possibility of weakened lung immunity after stroke. The focus of this...

Industry-Academia PhD Position New tools for immunopeptidomics An opportunity for an outstanding PhD candidate to undertake a collaborative...

People may develop epilepsy at any time throughout their life, and there are many different causes of epilepsy. This study will identify whether...
Supervisor: Dr Emma Foster

Direct clinical relevance: high. Hands-on learning opportunities: Various aspects of work with mice and or human specimens, workup of tissues for...
Supervisor: Prof Claudia Nold

Therapies that enhance the immune response to tumours have revolutionised the management of cancer. However, most tumours do not have a high...

Background: Mitochondria are energy-producing organelles. They form a network inside cells, and their health is critical to cell function....
Supervisor: Dr Georg Ramm

Artificial Intelligence for the Prediction and Evolutionary Modelling of Chronic Subdural Haematoma Progression

Natural killer (NK) cells are innate lymphocytes that play a vital role in the immune response through their ability to directly kill transformed and...

The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of...

Chronic cough affects about 10% of the global population with significant socioeconomic burden. Currently available therapeutic agents are not...
Supervisor: Dr Aung Aung Kywe Moe

Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, cancer, and metabolic diseases. Initially,...
Supervisor: Dr Wael Awad

Medical health records are essential tools for documenting patients' medical histories. Standardizing these records is crucial because it allows...
Supervisor: Prof. Sergio Uribe

Inflammatory bowel disease is a chronic immune mediated disorder affecting the intestine with no known cure. The pathogenesis of this disease results...
Supervisor: Dr Rimma Goldberg

Inflammatory pathways are a key contributor to diabetic vascular disease, including atherosclerosis. Underlying the development of vascular disease...

Huntington’s disease (HD) is a fatal inherited neurodegenerative disorder, causing progressive brain degeneration, cognitive and motor impairment....

Obstructive sleep apnoea (OSA) is characterized by repetitive collapse (apnoea) or partial collapse (hypopnoea) of the pharyngeal airway during sleep...

The Mediator complex with its catalytic subunit the Mediator kinase module, composed of CDK8/19 and other members, is multimeric complex regulating...
Supervisor: Dr Marius Dannappel

HIV infection has a substantial impact on immune cells, and whilst many of these effects are improved after starting anti-HIV therapy, they are often...
Supervisor: Dr Anna Hearps

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