Research Projects
Preliminary data from the Nguyen-Daly lab has identified Fibroblast growth factor receptors (FGFRs) as promising therapeutic targets for triple-...
Supervisor: Dr Lan Nguyen
Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, metabolic diseases, and cancer. Namely,...
Supervisor: Dr Wael Awad
The gastric carcinogenic bacterium Helicobacter pylori has a unique ability to withstand high acidity of the stomach by buffering its periplasm at pH...
Supervisor: Assoc Professor Anna Roujeinikova
In several cancer types, a higher tumour mutational burden (TMB) has been associated with increased immune cell infiltration into tumours and better...
Supervisor: Professor Nicholas Huntington
The discovery of giant viruses, comparable in size and complexity to simple cellular organisms has pushed back the frontier of the virus world....
Supervisor: Assoc Professor Fasseli Coulibaly
The Hippo/YAP signalling pathway is frequently dysregulated (~80%) in breast cancer. Yet, efforts aimed at targeting this pathway for therapeutic...
Supervisor: Dr Lan Nguyen
The human genome is dominated by non-protein encoding information. Indeed, the differences between humans and other animals cannot be accounted for...
Supervisor: A/Prof Traude Beilharz
Small cell lung cancer (SCLC) is an incredibly aggressive form of lung cancer with limited treatment options, begging the need for major
therapeutic...
Supervisor: Professor Nicholas Huntington
Our group focuses of studying dendritic cells (DC) by analysing the cell surface receptors they express with the view that these receptors contribute...
Supervisor: Assoc Professor Irene Caminschi
The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...
Supervisor: Assoc Professor Michelle Dunstone
The eukaryotic genome consists of two classes of genes preceded by distinctly different promoter sequences. Housekeeping genes (90%) code for...
Supervisor: Dr Hans Elmlund
Gastric cancer is a leading cause of cancer-related death, claiming more than 1 million lives annually. A major predisposing factor to developing...
Supervisor: Dr Dustin Flanagan
Developing tumour cells interact with a complex and heterogeneous ecosystem, namely the tumour microenvironment (TME), comprising mutant and wild-...
Supervisor: Dr Dustin Flanagan
To be able to stave off infections and cancers throughout life, our immune systems first need to recognise and tolerate the ~200 different cell types...
Supervisor: Dr Stephen Daley
Cancer cells can acquire stromal or developmental-like phenotypes allowing them to masquerade as other cell types, making the challenge of...
Supervisor: Dr Dustin Flanagan
The adaptive arm of immune system uses lymphocytes to generate antibody and memory responses to challenges throughout life. Three lineages of...
Supervisor: Dr Martin Davey
The adaptive arm of immune system uses lymphocytes to generate antibody and memory responses to challenges throughout life. Three lineages of...
Supervisor: Dr Martin Davey
Tumour formation and progression are driven by widespread changes in gene regulation. We have combined machine learning with gene co-expression...
Supervisor: Dr David Goode
RNA sequencing technologies enable the simultaneous detection of tens of thousands of genes, providing researchers with a powerful tool for...
Supervisor: Professor Wei Shi
The food intake of the mother during gestation and the breastfeeding period has far-reaching consequences for the development of the child and their...
Supervisor: Dr. Asolina Braun