Description
This project is part of the RNA Systems Biology Lab's ambition to de-risk discovery and translational research using a novel RNA-seq based digital fingerprinting method predictive of eukaryotic cell fate. As proof of concept, this project will test a new bioinformatically informed set of biomarkers of metastatic potential in cancer cell lines, biopsy tissue and/or organoids. The research will involve a high-content cell growth, treatment, sampling, and an RNA-sequencing strategy to validate (or reject) our current biomarker candidates. Any new data will be bioinformatically mined for additional candidate signatures of metastatic potential. The project will suit students with a background in Biochemistry, Genetics and Cell Biology, but most importantly requires a desire to learn the panning and organisational skills needed for high-content research. Wet-lab and dry-lab (Bioinformatic) projects are available.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
RNA-seq, Cancer Metastasis, Biomarker discovery, Bioinformatics,
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Biochemistry and Molecular Biology
Available options
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Short projects
Joint PhD/Exchange Program
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
15 Innovation Walk