Research Projects
This is a qualitative study looking at how children's lives are impacted by having a parent with functional seizures.
Supervisor: Dr Lana Higson
**New Projects On Offer for 2025**
Metabolic memory is the name given to the phenomenon whereby previous exposure to metabolic perturbations has...
Supervisor: Professor Sam El-Osta
Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...
Supervisor: Assoc Professor Margaret Hibbs
Epilepsy is complex brain disorder, and many patients are not adequately treated with existing therapies. New therapeutic avenues are needed, such as...
Supervisor: Assoc Professor Nigel Jones
Socioeconomically advantaged people with multiple sclerosis have far milder disability compared to disadvantaged people, even accounting for...
Supervisor: Dr Anna He
The Optimise Study is a multiplatform study exploring the impact of COVID-19 on the community; this includes assessing the communities understanding...
Supervisor: Professor Margaret Hellard
Post-traumatic epilepsy (PTE) accounts for 20% of symptomatic epilepsy. Despite multiple studies have identified male sex as one of the risk factors...
Supervisor: Dr. Runxuan Lin
Brain inflammation appears to play a critical role in the pathogenesis of epilepsy. A major cell type involved in inflammatory cascades are the...
Supervisor: Assoc Professor Nigel Jones
Oesophageal function is complex and various methods have been developed to assess this. Oesophageal manometry, which involves synchronous recording...
Supervisor: Dr Paul Burton
The development of diabetic complications including vascular and renal disease is enhanced in diabetic patients. However, the underlying mechanism as...
Supervisor: Dr Jay C. Jha
The management of gut disorders, including irritable bowel syndrome, involves complex interactions between biological, psychological, and contextual...
Supervisor: Assoc Prof Heidi Staudacher
The skin microbiome is a key component of barrier immunity and may influence inflammatory skin disease, wound healing, burns, skin transplantation...
Supervisor: Celine Pattaroni
Background: Current MR antagonists are among the most effective therapies for heart failure, yet their use remains constrained by adverse renal...
Supervisor: Professor Morag J. Young
Project overview: Plasminogen activation plays a key role in fibrinolysis, which is the process of blood clot removal. Plasminogen is an inactive...
Supervisor: Professor Robert Medcalf
This project seeks to further improve the behavior of our prototype peptide inhibitor CHA-061 against the profibrotic effect of CDA1. CHA-061 is a...
Supervisor: Dr Zhong-Lin Chai
Despite an increase in the number of women with severe mental illness desiring families and a subsequent increase in the rate of antenatal...
Supervisor: Professor Jayashri Kulkarni
Most neurological disorders, e.g. Alzheimer's, Parkinson's Disease, etc.. are associated with the build up of toxic proteins, which can...
Supervisor: Dr Ben Sinclair
There is accumulating evidence that diet can play a key role in improving depressive symptoms. The most compelling evidence so far is for traditional...
Supervisor: Assoc Prof Heidi Staudacher
Characterising donor specific B cells and how this relates to transplantation outcomes.
Supervisor: Prasanti Kotagiri
There is no defined optimal treatment for functional cognitive disorders (FCD), despite effective treatments being desperately needed. This research...
Supervisor: Dr Lana Higson