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Research Projects

Background: Mitochondria are energy-producing organelles. They form a network inside cells, and their health is critical to cell function....
Supervisor: Dr Georg Ramm

Natural killer (NK) cells are innate lymphocytes that play a vital role in the immune response through their ability to directly kill transformed and...

The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of...

Metabolite based T cell immunity is emerging as a major player in antimicrobial immunity, autoimmunity, cancer, and metabolic diseases. Initially,...
Supervisor: Dr Wael Awad

Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly

Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose

One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...

Background Nuclear transport is central to eukaryotic cell processes such as signal transduction and differentiation, where changes in transcription...
Supervisor: Professor David Jans

Nuclear transport inhibitors to combat diseases Two major health burdens world-wide are cancer and infectious diseases like viral illnesses and...
Supervisor: Professor David Jans

Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott

Primary liver cancer is one of the world’s deadliest cancers and the third most common cause of cancer death. Hepatocellular carcinoma (HCC)...

Cubosomes have attracted widespread attention in the pharmaceutical industry due to their high stability, ability to contain amphiphilic drugs,...

Oligodendrocytes play a vital role as supporting cells within the central nervous system, aiding in signal transmission among a plethora of other...
Supervisor: Yasith Mathangasinghe

Advanced age is the strongest risk factor for cancer development, with 1 in 2 persons developing cancer by age 85. Despite being a strong predictor...
Supervisor: Dr Lochlan Fennell

Frequent resistance to single-agent treatment means that doctors are turning to combination therapy, i.e. ‘cocktails of drugs’, to beat resistance....
Supervisor: Dr Lan Nguyen

This project aims to engineer new biomaterials that can permanently integrate with the brain. This project expects to generate new knowledge using...

The Victorian Heart Institute (VHI) is seeking a highly motivated student to conduct a systematic review on personalised medicine in cardiovascular...
Supervisor: Dr Denuja Karunakaran

Every ageing woman faces potentially debilitating physical symptoms following the cessation of ovarian function at menopause. Crucially, many of...
Supervisor: Dr Kelly Walton

Gonadal-derived inhibin A and inhibin B are essential factors in mammalian reproduction, negatively regulating pituitary production of follicle...

This project aims to determine how antibiotic resistance and toxin plasmids are replicated and maintained in this important bacterial pathogen
Supervisor: E/Prof Julian Rood

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