Research Projects
Monoclonal antibodies (mAbs) that block checkpoint inhibitory receptors including Programmed Death (PD)-1 act directly on T cells to overcome ‘...
Supervisor: Assoc Professor Meredith O'Keeffe
Recently, novel genetic variants of GPR75 were discovered to be associated with leanness in large genome wide associated studies. This is the first...
Supervisor: Professor Zane Andrews
Small noncoding RNAs are increasingly recognised as important regulators of gene expression and genome integrity across all kingdoms of life. This is...
Supervisor: Dr Peter Boag
The tyrosine kinase Src was the first proto-oncogene to be identified, and it is now known that Src plays an important role in several human cancers...
Supervisor: Professor Roger Daly
Dysfunctional feeding behaviour encompasses energy overconsumption (obesity, binge eating) to malnutrition (unhealthy food choices, excessive dieting...
Supervisor: Professor Zane Andrews
Please note: unfortunately no funding is available to support Masters projects.
We are performing in-depth characterization of the...
Supervisor: A/Prof. Anne Fletcher
The oocyte-secreted TGF-beta proteins, BMP15 and GDF9, are essential for the acquisition of oocyte developmental competence during folliculogenesis....
Supervisor: Assoc Professor Craig Harrison
Single cell technologies are being rapidly adopted and accordingly, there is a high demand for intuitive tools and software that help with the...
Supervisor: Professor Nicholas Huntington
Natural killer (NK) cells are effector lymphocytes of the innate immune system that are known for their ability to kill transformed and virus-...
Supervisor: Professor Nicholas Huntington
Mitochondria supply the cell with energy by generating ATP, but they are highly susceptible to damage. Mitophagy, the process by which damaged...
Supervisor: Dr. Sylvain Trépout
When mitochondria are unable to function properly, the proteome changes to re-establish homeostasis. In this project, we will investigate why some...
Supervisor: Dr Luke Formosa
Iron is essential for bacterial growth, but it is severely limited in most environments. Bacteria have evolved clever systems to acquire this...
Supervisor: Dr Francesca Short
Trauma and uncontrolled bleeding is a major cause of morbidity worldwide. We have developed and structurally characterized potent monoclonal...
Supervisor: Professor James Whisstock
Mitochondrial complex I (CI) dysfunction underlies devastating pediatric disorders such as Leigh Syndrome and contributes to age-associated...
Supervisor: Associate Professor James Letts
Pseudomonas aeruginosa is a Gram-negative bacterium that is one of the most common pathogens of people with cystic fibrosis. This organism causes...
Supervisor: Professor John Boyce
Only a relatively small number of Australians cycle regularly, and many people point to concerns about safety, comfort, and the quality of...
Supervisor: Dr Joanne Caldwell
Pulmonary hypertension is a disease of high blood pressure in the lungs, which leads to increased right ventricular afterload, remodelling and...
Supervisor: Dr Kristen Bubb
The Mpox virus is endemic in West and Central African countries. In 2022, the WHO declared Mpox a global health emergency as infections have spread...
Supervisor: Dr Gabriela Khoury
The project will use live cell imaging, molecular cell biology and infection models to understand how Candida albicans evades innate immune...
Supervisor: Assoc Professor Ana Traven
Complex I of the mitochondrial respiratory chain is a huge machine containing 44 different subunits. Following up on recent studies, (Formosa et al...
Supervisor: Dr Luke Formosa