Research Projects
Pleurotolysin: a pore forming toxin from the carnivorous oyster mushroom
Supervisor: Assoc Professor Michelle Dunstone
Putting the brakes on inflammation: Using the structure of important immune protein receptors to develop therapeutics
Supervisor: Assoc Professor Michelle Dunstone
The sheer mechanical power of shark jaws, combined with an increase in shark bites in Australia since the 2000s, have accelerated the need for the...
Supervisor: Dr Olga Panagiotopoulou
Over the past years, our scientific and clinical research team has pursued basic discovery and preclinical research into the skin autoimmune disease...
Supervisor: Dr. Asolina Braun
Traditionally, neuroscience has relied on electrical and optical recordings to observe brain signals. The advent of optogenetics, genetic tools that...
Supervisor: Daisuke Shimaoka, Group Leader
The mineralocorticoid receptor (MR) is an established therapeutic target for heart disease. However current drugs are not selective for the heart and...
Supervisor: Professor Morag J. Young
Regulating the receptors: new targets for fine-tuning hormone receptor actions in health and disease
Steroid hormone receptors (nuclear receptors) are expressed in many tissues and act as transcription factors to control cellular and tissue function...
Supervisor: Professor Morag J. Young
Gamma-aminobutyric acid (GABA) produced by Glutamic Acid Descarboxylase (GAD) is the most abundant neurotransmitter inhibitor in the CNS and is...
Supervisor: Professor James Whisstock
The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...
Supervisor: Assoc Professor Jose Polo
Here we will combine omics technologies with novel muscle-specific gene manipulation technologies and resistance exercise training to discover novel...
Supervisor: A/Prof. Adam Rose
Plasmin (Plm) plays a crucial role in blood clot dissolution (fibrinolysis), inflammation, cellular migration and wound healing. Alpha2-antiplasmin (...
Supervisor: Dr Ruby Law
Natural killer (NK) cells are the founding members of the innate lymphoid cell family and contribute to the rapid production of inflammatory...
Supervisor: Professor Nicholas Huntington
The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...
Supervisor: Professor John Carroll
The Bcl-2 family of proteins is crucial for apoptosis (a form of programmed cell death) regulation. The Bcl-2 proteins are synthesized in cytosolic...
Supervisor: Professor Mibel Aguilar
Hypertension and its associated complications affect men and women during different stages of their lives. Our research is focusing on what controls...
Supervisor: Dr Katrina Colafella
Many critical biological targets remain “undruggable,” limiting treatment options for complex diseases. Our team addresses this challenge through AI-...
Supervisor: Dr. Cyntia Taveneau
Inflammation is the body’s response to injury or infection. A key feature of inflamed tissues is the accumulation of leukocytes (white blood cells),...
Supervisor: Assoc Professor Martin Stone
Obesity and overweight are major health concerns and a burden to public health in Australia, affecting 2 in 3 adults (12.5 million), and 1 in 4...
Supervisor: Professor Zane Andrews
Spatiotemporal dynamics of cortical network activity: the link between micro- and mesoscale activity
Spontaneous synchronization is a common phenomenon occurring in diverse contexts, from a group of glowing fireflies or chirping crickets in a field...
Supervisor: Dr Mehdi Adibi
We have identified specific sphingolipids that control brain development and protect the nervous system throughout life. This exciting project will...
Supervisor: Professor Roger Pocock