Reading and Writing Brain-Wide Dynamics Through Light

Traditionally, neuroscience has relied on electrical and optical recordings to observe brain signals. The advent of optogenetics, genetic tools that allow control of brain activity using light, has revolutionized the field by enabling precise manipulation of neural dynamics. This project aims to develop a system for simultaneous imaging and manipulation of brain activity across the entire brain. Once established, we will use it to control brain-wide oscillations during sleep and investigate the causal roles of individual brain regions. We welcome students who are comfortable working with rodents, are eager to learn animal surgery and physiological experimentation.