You are here

Research Projects

Klebsiella pneumoniae is a major cause of antibiotic resistant hospital-associated infections that can be extremely difficult to treat. The World...

Multi-drug resistance in Gram-negative bacteria (MDR-GNB) is a global health challenge that threatens many medical advances. Infections caused by MDR...
Supervisor: Dr Nenad Macesic

Single-chain antibodies against epitopes associated with vascular dysfunction / injury provide a unique tool for specific targeting of exosomes in...

Anti-HIV therapy suppresses HIV replication and prevents AIDS, however HIV currently cannot be cured and continuous, life-long therapy is required....
Supervisor: Dr Anna Hearps

Atherosclerosis is a major contributor to cardiovascular disease (CVD) related deaths in subjects with diabetes. Residual increased risk of CVD...
Supervisor: Dr Waheed Khan

Diabetic kidney disease is an important complication of diabetes and remains a huge medical burden and a major contributor of morbidity and mortality...

Leukaemia stem cells are thought to be the source of relapse following treatment with conventional therapies. New and emerging treatments are better...
Supervisor: Dr Omer Gilan

We are developing a platform for TCR and antibody-antigen discovery and engineering by conventional serology and T-cell assays, multiplex antigen...

Stroke is a leading cause of mortality and morbidity. Bacterial infections are one of the most common complications following stroke. Bacterial...
Supervisor: Dr Malcolm Starkey

Project overview: The serine protease tissue-type plasminogen activator (tPA) is well known for its fibrinolytic properties to remove blood clots...

The glymphatic system is the brain's method for clearing waste products to allow for appropriate functioning. In certain diseases, this system...

Viral hepatitis is responsible for more deaths globally than HIV and malaria, with hepatitis C virus (HCV) accounting for a third of viral hepatitis...

Despite the benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD), many patients do not access or complete pulmonary...
Supervisor: Dr Angela Burge

This is a qualitative study looking at how children's lives are impacted by having a parent with functional seizures.
Supervisor: Dr Lana Higson

**New Projects On Offer for 2025** Metabolic memory is the name given to the phenomenon whereby previous exposure to metabolic perturbations has...
Supervisor: Professor Sam El-Osta

Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...

Epilepsy is complex brain disorder, and many patients are not adequately treated with existing therapies. New therapeutic avenues are needed, such as...

Socioeconomically advantaged people with multiple sclerosis have far milder disability compared to disadvantaged people, even accounting for...
Supervisor: Dr Anna He

The Optimise Study is a multiplatform study exploring the impact of COVID-19 on the community; this includes assessing the communities understanding...

Post-traumatic epilepsy (PTE) accounts for 20% of symptomatic epilepsy. Despite multiple studies have identified male sex as one of the risk factors...
Supervisor: Dr. Runxuan Lin

Pages