Research Projects
Incomplete reporting of systematic reviews prevents users of the report from being able to fully interpret the findings and understand the...
Supervisor: Dr Matthew Page
Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly
Congenital syphilis, caused by mother to child transmission of syphilis, is the second leading cause of stillbirth globally. Definitive diagnosis of...
Supervisor: Dr Minh Pham
As malaria transmission continues to decline, even the most sensitive methods for determining prevalence via detection of the parasite become...
Supervisor: Professor Leanne Robinson
Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose
The formation of the head and face is a tightly regulated process, with variations from the genetic program leading to craniofacial defects. We have...
Supervisor: Dr. Jan Manent
Parkinson's disease (PD) is a debilitating neurodegenerative disorder that affects over 7 million people worldwide. Hallmark symptom of PD is...
Supervisor: Dr Joohyung Lee
Cardiovascular diseases (CVDs), principally ischemic heart disease including myocardial infarction (heart attacks) and stroke, are the leading cause...
Supervisor: Professor Karlheinz Peter
Malaria elimination/ eradication is a global commitment that is achievable but which will require the development of novel tools and approaches. This...
Supervisor: Dr Jack Richards
One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...
Supervisor: Professor Mibel Aguilar
Background:
Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence and is associated with high morbidity and mortality...
Supervisor: Assoc Professor Bing Wang
IMPDH2, an oncogene in various cancers, is a key rate-limiting enzyme in nucleotide synthesis, maintaining guanine-based nucleotides for nucleic acid...
Supervisor: Dr Gamze Kuser Abali
Background
Nuclear transport is central to eukaryotic cell processes such as signal transduction and differentiation, where changes in transcription...
Supervisor: Professor David Jans
Nuclear transport inhibitors to combat diseases
Two major health burdens world-wide are cancer and infectious diseases like viral illnesses and...
Supervisor: Professor David Jans
Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott
This project is examining nutrigenomics as a tool for prevention of cardiometabolic risk factors.
The candidate will have an opportunity to learn...
Supervisor: Professor Barbora De Courten
As the global population ages, it's increasingly important to understand the role of behavioral risk factors such as diet in disease prevention...
Supervisor: Holly Wild
Non-alcoholic fatty liver (NAFLD) disease effects more than 80% of obese patients. This disease is gaining increasing attention as independent driver...
Supervisor: Dr Paul Burton
Primary liver cancer is one of the world’s deadliest cancers and the third most common cause of cancer death. Hepatocellular carcinoma (HCC)...
Supervisor: Professor Tony Tiganis
Hepatocellular carcinoma (HCC) is one of the most fatal and fastest growing cancers. In recent years, non-alcoholic steatohepatitis (NASH) has been...
Supervisor: Professor Colby Zaph