Research Projects
People with underlying non-communicable disease have lower tolerance and worse outcomes to infections but we don't understand why. To begin to...
Supervisor: Dr Adam Rose
Some intermediary metabolic enzymes are upregulated in the liver of mice and humans with type 2 diabetes. Here we will test whether and how these...
Supervisor: Dr Adam Rose
Studies from lower order organisms such as flies and worms have shown that mild mitochondrial dysfunction invokes a stress response that promotes...
Supervisor: Dr Adam Rose
Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose
Here we will combine omics technologies with novel muscle-specific gene manipulation technologies to discover novel signalling pathways controlling...
Supervisor: Dr Adam Rose