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Research Projects

Brain stimulation is a powerful therapeutic approach for an increasing number of neuropsychiatric disorders. However, the exact mechanisms and ideal...
Supervisor: Dr Leonardo Gollo

This research project aims to generate patient-specific induced pluripotent stem cell (iPSC)-derived brain cells to model the effects of Type I...

Cardiovascular diseases (CVDs) are not only the leading cause of death in women but also contribute significantly to disability. Women with a history...
Supervisor: Dr Maureen Makama

The innate immune system is capable of intricately detailed detection, differentiation and elimination of pathogenic bacteria. However, the vast...

Metallo‐peptidases cleave amino acids from either the N‐ and C‐termini of peptide hormones to either generate or degrade biologically active peptides...

Fibroblasts in the lymph nodes are able to regulate differentiation and localization of innate and adaptive immune cells. They are also a primary...
Supervisor: Dr Kostas Knoblich

Many cancers display differences in incidence, prognosis, and treatment response between males and females. In most cases, it is not well understood...
Supervisor: Dr Miles Andrews

Interleukin (IL)-37 was discovered in silico in 2000, but received very little attention (not even 10 publications) in general and nothing at all was...
Supervisor: Professor Marcel Nold

TCR recognition of peptide + MHC class I complexes (pMHCI) is central to CD8+ T cell function. It is clear that the nature of the TCR-pMHCI...

This project focuses on the basic and translational research of cancer, inflammation and thrombosis. We design, test and implement novel nano-/...

DC take up, process and present antigen (Ag) to T cells to initiate immune responses. There are multiple DC subsets that are tailored for different...

Granulosa cell tumours (GCT) of the ovary are endocrine tumours that both make and respond to hormones. We have recently confirmed a key mutation in...

Monash Live-Biobanking & Precision Cancer Immunotherapy (MoLBi-PCI): From Bench to Precision Therapies

The use of genetic test results in insurance raises ethical, legal and social concerns. The issue is one of the most significant ethical, legal and...
Supervisor: Professor Paul Lacaze

Anorexia nervosa (AN) has the highest mortality rate of any psychiatric disorder - 12 times higher than the death rate from all other causes in...
Supervisor: Dr Claire Foldi

The ability of the adult nervous system to adapt/remodel across the lifespan (and importantly after stroke) offers potential for brain recovery...
Supervisor: Dr Sharon Kramer

Moya moya disease natural history study

This project involves the translation of findings from mouse models of inflammatory bowel disease (IBD) to human patients, both with IBD and healthy...
Supervisor: A/Prof Edward Giles

Evidence from small studies or limited locations is not robust and generalisable. This project will use a world largest data on mortality and...
Supervisor: Professor Yuming Guo

Strengthening routine surveillance of infectious diseases is a high priority in Papua New Guinea (PNG). A major challenge is the lack of cost-...

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