Research Projects
Frequent resistance to single-agent treatment means that doctors are turning to combination therapy, i.e. ‘cocktails of drugs’, to beat resistance....
Supervisor: Dr Lan Nguyen
This project aims to engineer new biomaterials that can permanently integrate with the brain. This project expects
to generate new knowledge using...
Supervisor: Professor Mibel Aguilar
Pleurotolysin: a pore forming toxin from the carnivorous oyster mushroom
Supervisor: Assoc Professor Michelle Dunstone
Putting the brakes on inflammation: Using the structure of important immune protein receptors to develop therapeutics
Supervisor: Assoc Professor Michelle Dunstone
Over the past years, our scientific and clinical research team has pursued basic discovery and preclinical research into the skin autoimmune disease...
Supervisor: Dr. Asolina Braun
Gamma-aminobutyric acid (GABA) produced by Glutamic Acid Descarboxylase (GAD) is the most abundant neurotransmitter inhibitor in the CNS and is...
Supervisor: Professor James Whisstock
Here we will combine omics technologies with novel muscle-specific gene manipulation technologies to discover novel signalling pathways controlling...
Supervisor: Dr Adam Rose
Natural killer (NK) cells are the founding members of the innate lymphoid cell family and contribute to the rapid production of inflammatory...
Supervisor: Professor Nicholas Huntington
The Bcl-2 family of proteins is crucial for apoptosis (a form of programmed cell death) regulation. The Bcl-2 proteins are synthesized in cytosolic...
Supervisor: Professor Mibel Aguilar
Inflammation is the body’s response to injury or infection. A key feature of inflamed tissues is the accumulation of leukocytes (white blood cells),...
Supervisor: Assoc Professor Martin Stone
Eukaryotic transcriptional co-activators are multi-subunit complexes that both modify chromatin and recognize histone modifications to control gene...
Supervisor: Dr Dominika Elmlund
The immune system comprises a variety of effector cells that are uniquely poised to recognize infected or transformed cells. However, the capacity of...
Supervisor: Dr Richard Berry
Viruses and pathogens are part of day-to-day encounters that the immune system needs to deal with. How the immune system “sees”, recognises and...
Supervisor: Assoc Professor Stephanie Gras
In this project, in collaboration with Professor Ross Hannan (ANU), we will study the structure of Upstream Binding Factor (UBF) in complex with...
Supervisor: Professor James Whisstock
SAGA’s many functions are essential for normal embryo development in flies and mice. Mutation or altered expression of SAGA subunits are associated...
Supervisor: Dr Hans Elmlund
Like many developed countries, the population of Australia is ageing; with 13.8% of the population currently over the age of 65 and predictions this...
Supervisor: Professor Nicole La Gruta
Post-translational modification of joint proteins leads to the generation of autoantigenic peptides that drive the inflammatory response in...
Supervisor: Dr Hugh Reid
In celiac disease (CD), the T cell response to gliadin peptides derived from gluten in from wheat, barley and rye has been well characterised....
Supervisor: Dr Hugh Reid
Viruses and humans have coevolved for millions of years and during this time viruses have armed themselves with strategies to hijack or evade our...
Supervisor: Dr Natalie Borg
DC monitor the environment for potential “danger signals” that signify pathogen invasion, including non-homeostatic cell death caused by viruses. We...
Supervisor: Assoc Professor Mireille Lahoud