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Research Projects

Sodium ions play a central role in membrane transport and cell homeostasis. Increased sodium concentration has been observed in brain tumors as well...

Frontotemporal dementia (FTD) is generally due to abnormalities either in a protein called tau (45%) or a protein called TDP-43 (45%). In both types...

Behavioural variant fronto-temporal dementia (bvFTD) is the second most common form of dementia in people under 65. It is characterised by loss of...
Supervisor: Dr Lucy Vivash

Progressive supranuclear palsy (PSP) is a rare movement disorder that presents in late middle age. Currently there are no treatments for PSP, with...
Supervisor: Dr Lucy Vivash

Epilepsy is a serious neurological condition which is characterised by spontaneous seizures, or 'fits'. Current medications are effective...

In October 2016, we changed our treatment policy by not treating these individuals on the day of testing unless they present with symptoms or the...

Antimicrobial resistance (AMR) is an urgent global health challenge that threatens our healthcare system and many of the advances of modern medicine...
Supervisor: Dr Nenad Macesic

Single-chain antibodies against epitopes associated with vascular dysfunction / injury provide a unique tool for specific targeting of exosomes in...

The adhesion of leukocytes to endothelium plays a central role in the development of atherosclerosis and thus represents an attractive therapeutic...

Background: Stroke occurs as a result of brain injury due to obstructed blood flow (ischaemia) or unrestricted bleeding in the brain (haemorrhage...

Background: Allogeneic stem cell transplantation (allo-HSCT) is used to ‘cure’ blood cancers. However, it leads to graft-versus-host disease (GVHD...

Diabetic kidney disease is an important complication of diabetes and remains a huge medical burden and a major contributor of morbidity and mortality...

Background: Tissue remodelling, characterised by the deposition of collagen, follows inflammation and is a fundamental step in wound repair. However...

The academic research program within this laboratory is focused on gaining an improved understanding of how helminth parasites and commensal bacteria...

AML is an aggressive blood cancer with dire prognosis due to disease relapse initiated by therapeutically-resistant Leukaemia Stem Cells (LSCs)....

The ‘Australian COVID-19 Frontline Health Workers Study’ is the largest, national, cross-sectional study examining psychosocial distress in frontline...

The earliest humoral immune cells that develop in mammals are B1 cells, responding to and producing antibodies against commensal organisms and self...
Supervisor: Dr Marcus Robinson

Cardiovascular disease remains a leading course of morbidity and mortality following an acute coronary syndrome. Despite optimal medical therapy,...
Supervisor: Dr Jamie Layland

Chronic treatment with anti-epileptic drugs (AEDs) is known to produce a number of side effects in patients. For approximately 35% of patients long...
Supervisor: Dr Lucy Vivash

The system that is responsible for the clearance of macroscopic waste from the central nervous system is the glymphatic system. This waste removal...

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