Research Projects
Leukaemia stem cells are thought to be the source of relapse following treatment with conventional therapies. New and emerging treatments are better...
Supervisor: Dr Omer Gilan
We are developing a platform for TCR and antibody-antigen discovery and engineering by conventional serology and T-cell assays, multiplex antigen...
Supervisor: A/Prof Vivek Naranbhai
The glymphatic system is the brain's method for clearing waste products to allow for appropriate functioning. In certain diseases, this system...
Supervisor: Assoc Professor Nigel Jones
Viral hepatitis is responsible for more deaths globally than HIV and malaria, with hepatitis C virus (HCV) accounting for a third of viral hepatitis...
Supervisor: Doctor Rachel Sacks-Davis
Urinary tract infections are highly prevalent, afflicting over 400 million people globally each year. The most common cause is uropathogenic E. coli...
Supervisor: Dr Malcolm Starkey
**New Projects On Offer for 2025**
Metabolic memory is the name given to the phenomenon whereby previous exposure to metabolic perturbations has...
Supervisor: Professor Sam El-Osta
Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...
Supervisor: Assoc Professor Margaret Hibbs
Epilepsy is complex brain disorder, and many patients are not adequately treated with existing therapies. New therapeutic avenues are needed, such as...
Supervisor: Assoc Professor Nigel Jones
The Optimise Study is a multiplatform study exploring the impact of COVID-19 on the community; this includes assessing the communities understanding...
Supervisor: Professor Margaret Hellard
Post-traumatic epilepsy (PTE) accounts for 20% of symptomatic epilepsy. Despite multiple studies have identified male sex as one of the risk factors...
Supervisor: Dr. Runxuan Lin
Brain inflammation appears to play a critical role in the pathogenesis of epilepsy. A major cell type involved in inflammatory cascades are the...
Supervisor: Assoc Professor Nigel Jones
Oesophageal function is complex and various methods have been developed to assess this. Oesophageal manometry, which involves synchronous recording...
Supervisor: Dr Paul Burton
The development of diabetic complications including vascular and renal disease is enhanced in diabetic patients. However, the underlying mechanism as...
Supervisor: Dr Jay C. Jha
This project seeks to further improve the behavior of our prototype peptide inhibitor CHA-061 against the profibrotic effect of CDA1. CHA-061 is a...
Supervisor: Dr Zhong-Lin Chai
Despite an increase in the number of women with severe mental illness desiring families and a subsequent increase in the rate of antenatal...
Supervisor: Professor Jayashri Kulkarni
Epilepsy is one of the most common serious chronic neurological disorders and is estimated to affect approximately 68 million people worldwide....
Supervisor: Professor Patrick Kwan
Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. Recent studies suggest...
Supervisor: Assoc Professor Margaret Hibbs
Inborn Errors of Immunity (IEIs) are caused by rare genetic variants. Despite of major advances in genetics, in many patients no rare causative...
Supervisor: Dr Emily Edwards
Cancer is a heterogeneous disease, with differences not only among different patients, but even amongst the bulk of cells within tumors in individual...
Supervisor: Dr Mark Shackleton
Based at the Central Clinical School, our laboratory works closely with clinicians at the Alfred Hospital to study mechanisms of cancer development...
Supervisor: Dr Gamze Kuser Abali