Research Projects
The bladder is a unique and often forgotten mucosal site. When the bladder is exposed to bacterial pathogens it sheds superficial epithelial cells to...
Supervisor: Dr Malcolm Starkey
We are developing a platform for TCR and antibody-antigen discovery and engineering by conventional serology and T-cell assays, multiplex antigen...
Supervisor: A/Prof Vivek Naranbhai
The glymphatic system is the brain's method for clearing waste products to allow for appropriate functioning. In certain diseases, this system...
Supervisor: Assoc Professor Nigel Jones
Viral hepatitis is responsible for more deaths globally than HIV and malaria, with hepatitis C virus (HCV) accounting for a third of viral hepatitis...
Supervisor: Doctor Rachel Sacks-Davis
Despite the benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD), many patients do not access or complete pulmonary...
Supervisor: Dr Angela Burge
This is a qualitative study looking at how children's lives are impacted by having a parent with functional seizures.
Supervisor: Dr Lana Higson
**New Projects On Offer for 2025**
Metabolic memory is the name given to the phenomenon whereby previous exposure to metabolic perturbations has...
Supervisor: Professor Sam El-Osta
Bronchopulmonary dysplasia (BPD) is a severe lung disease that is the main cause of disability and death in premature infants. We have discovered...
Supervisor: Assoc Professor Margaret Hibbs
Epilepsy is complex brain disorder, and many patients are not adequately treated with existing therapies. New therapeutic avenues are needed, such as...
Supervisor: Assoc Professor Nigel Jones
The Optimise Study is a multiplatform study exploring the impact of COVID-19 on the community; this includes assessing the communities understanding...
Supervisor: Professor Margaret Hellard
Post-traumatic epilepsy (PTE) accounts for 20% of symptomatic epilepsy. Despite multiple studies have identified male sex as one of the risk factors...
Supervisor: Dr. Runxuan Lin
Brain inflammation appears to play a critical role in the pathogenesis of epilepsy. A major cell type involved in inflammatory cascades are the...
Supervisor: Assoc Professor Nigel Jones
Oesophageal function is complex and various methods have been developed to assess this. Oesophageal manometry, which involves synchronous recording...
Supervisor: Dr Paul Burton
The development of diabetic complications including vascular and renal disease is enhanced in diabetic patients. However, the underlying mechanism as...
Supervisor: Dr Jay C. Jha
This project seeks to further improve the behavior of our prototype peptide inhibitor CHA-061 against the profibrotic effect of CDA1. CHA-061 is a...
Supervisor: Dr Zhong-Lin Chai
Despite an increase in the number of women with severe mental illness desiring families and a subsequent increase in the rate of antenatal...
Supervisor: Professor Jayashri Kulkarni
Most neurological disorders, e.g. Alzheimer's, Parkinson's Disease, etc.. are associated with the build up of toxic proteins, which can...
Supervisor: Dr Ben Sinclair
There is accumulating evidence that diet can play a key role in improving mental health. The most compelling evidence so far is for traditional diet...
Supervisor: Assoc Prof Heidi Staudacher
Characterising donor specific B cells and how this relates to transplantation outcomes.
Supervisor: Prasanti Kotagiri
There is no defined optimal treatment for functional cognitive disorders (FCD), despite effective treatments being desperately needed. This research...
Supervisor: Dr Lana Higson