Research Projects
Inflammation in the lung is critical for host defence against viruses. However, excessive inflammation and immunopathology are characteristic...
Supervisor: Associate Professor Michelle Tate
Self-reactive T cells cause many autoimmune diseases, and can also trigger serious autoimmune side-effects in cancer patients undergoing...
Supervisor: Assoc Professor Ross Dickins
We manage the Australian Autoinflammatory Disease Registry (AADRY.org), and collaborate widely to identify genetic variants that may be the cause of...
Supervisor: Prof Seth Masters
Incomplete reporting of systematic reviews prevents users of the report from being able to fully interpret the findings and understand the...
Supervisor: Dr Matthew Page
Inflammatory Bowel Disease (IBD), predominantly Crohn’s Disease (CD) and Ulcerative Colitis (UC), is a chronic inflammatory condition of unknown...
Supervisor: A/Prof Edward Giles
Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly
Congenital syphilis, caused by mother to child transmission of syphilis, is the second leading cause of stillbirth globally. Definitive diagnosis of...
Supervisor: Dr Minh Pham
As malaria transmission continues to decline, even the most sensitive methods for determining prevalence via detection of the parasite become...
Supervisor: Professor Leanne Robinson
Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose
Stroke is a global leading cause of death and disability. Despite this, there is currently no treatment to limit inflammatory events which has been...
Supervisor: Associate Professor Connie Wong
The formation of the head and face is a tightly regulated process, with variations from the genetic program leading to craniofacial defects. We have...
Supervisor: Dr. Jan Manent
Parkinson's disease (PD) is a debilitating neurodegenerative disorder that affects over 7 million people worldwide. Hallmark symptom of PD is...
Supervisor: Dr Joohyung Lee
Cardiovascular diseases (CVDs), principally ischemic heart disease including myocardial infarction (heart attacks) and stroke, are the leading cause...
Supervisor: Professor Karlheinz Peter
One of the most recognised risk factors for cardiovascular disease is hypertension. Cardiac fibrosis is at the centre of many pathological conditions...
Supervisor: Professor Mibel Aguilar
Background:
Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence and is associated with high morbidity and mortality...
Supervisor: Assoc Professor Bing Wang
IMPDH2, an oncogene in various cancers, is a key rate-limiting enzyme in nucleotide synthesis, maintaining guanine-based nucleotides for nucleic acid...
Supervisor: Dr Gamze Kuser Abali
Background
Nuclear transport is central to eukaryotic cell processes such as signal transduction and differentiation, where changes in transcription...
Supervisor: Professor David Jans
Nuclear transport inhibitors to combat diseases
Two major health burdens world-wide are cancer and infectious diseases like viral illnesses and...
Supervisor: Professor David Jans
Bacteria are embroiled in a constant struggle with virulent bacteriophages. This battle for survival spans millions of years of evolution. Throughout...
Supervisor: Dr Gavin Knott
Women are recommended to have a 6-8 postnatal check after having a baby, usually with their general practitioner (GP). Whilst there is an expectation...
Supervisor: Dr Jessica Botfield