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Research Projects

Klebsiella pneumoniae is a major cause of antibiotic resistant hospital-associated infections that can be extremely difficult to treat. The World...

Multi-drug resistance in Gram-negative bacteria (MDR-GNB) is a global health challenge that threatens many medical advances. Infections caused by MDR...
Supervisor: Dr Nenad Macesic

Neurogenesis describes the fundamental process of generating neurons that integrate into existing circuits. Although originally thought to cease...

This is a knowledge translation project for the physiotherapy management of people with bronchiectasis. Following the development of the...
Supervisor: Dr Annemarie Lee

Background: Informal settlements are home to more than a billion people. This number is growing annually in low and middle-income countries such as...
Supervisor: Dr Rebekah Henry

Single-chain antibodies against epitopes associated with vascular dysfunction / injury provide a unique tool for specific targeting of exosomes in...

Cancer cachexia is a life-threatening condition characterised by a progressive loss of skeletal muscle and fat mass. Up to 80% of patients with...

Atherosclerosis, the process by which fats, cholesterol and other substances build up in the artery wall, is the leading cause of CV disease. This...
Supervisor: Dr Kristen Bubb

The global threat from antimicrobial resistance (AMR) was highlighted by the World Health Organization in its first-ever priority pathogen list of...
Supervisor: Dr Meiling Han

Anti-HIV therapy suppresses HIV replication and prevents AIDS, however HIV currently cannot be cured and continuous, life-long therapy is required....
Supervisor: Dr Anna Hearps

Atherosclerosis is a major contributor to cardiovascular disease (CVD) related deaths in subjects with diabetes. Residual increased risk of CVD...
Supervisor: Dr Waheed Khan

Inflammation-induced brain injury remains one of the main causes of disability after premature birth. There is no effective treatment. The pro-...
Supervisor: Dr Robert Galinsky

Diabetic kidney disease is an important complication of diabetes and remains a huge medical burden and a major contributor of morbidity and mortality...

Leukaemia stem cells are thought to be the source of relapse following treatment with conventional therapies. New and emerging treatments are better...
Supervisor: Dr Omer Gilan

This project aims to develop novel antisense oligonucleotides as an efficient and common therapeutic for targeting the polymyxin resistant gram-...
Supervisor: Dr Nitin Patil

The transcript encoding the proto-oncogene MYC is commonly overexpressed in prostate cancer (PC). MYC protein abundance is also increased in the...
Supervisor: Dr Luc Furic

Hypertension is a major cause of heart failure, heart attacks and strokes. Associated with the development of hypertension is the accumulation of...

Pulmonary hypertension (PH) is an incurable disease and a major cause of death and illness throughout the world. Whilst there has been advancement...

Systemic lupus erythematosus (SLE) and related autoimmune diseases remain incurable, with therapies largely directed at suppressing downstream...
Supervisor: Prof Michael Gantier

We are developing a platform for TCR and antibody-antigen discovery and engineering by conventional serology and T-cell assays, multiplex antigen...

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