Research Projects
For the majority of Intersex cases the underlying genetic aetiology is unknown. In males Sox9 is a critical ‘hub’ gene involved in sexual development...
Supervisor: Professor Vincent Harley
Male and female brains differ in anatomy and chemistry The prevailing dogma that oestrogen is the key factor involved in brain sex differentiation...
Supervisor: Professor Vincent Harley
Differences of sex development include sex chromosome aneuploidies such as Turner syndrom (TS) and Klinefelter syndrome (KS). Women with TS lack one...
Supervisor: Professor Vincent Harley
Intersex conditions are congenital conditions where gonadal or anatomical sex is atypical. Intersex conditions encompass a wide range of...
Supervisor: Professor Vincent Harley
The Harley laboratory has identified a sex reversed XY female patient with early onset Parkinson’s disease (PD). Through whole exome sequencing, it...
Supervisor: Professor Vincent Harley
Many diseases show sex differences in incidence, progression or age of onset. Furthermore, treatment of diseases
differs between the sexes, with...
Supervisor: Professor Vincent Harley
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder, triggered by the death of dopamine neurons in the brain region known as the...
Supervisor: Professor Vincent Harley
Gender identity is the gender with which a person identifies. Studies suggest that gender identity is affected by genetic, prenatal hormonal and/or...
Supervisor: Professor Vincent Harley