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Research Projects

Medical health records are essential tools for documenting patients' medical histories. Standardizing these records is crucial because it allows...
Supervisor: Prof. Sergio Uribe

Inflammatory bowel disease is a chronic immune mediated disorder affecting the intestine with no known cure. The pathogenesis of this disease results...
Supervisor: Dr Rimma Goldberg

Inflammatory pathways are a key contributor to diabetic vascular disease, including atherosclerosis. Underlying the development of vascular disease...

Huntington’s disease (HD) is a fatal inherited neurodegenerative disorder, causing progressive brain degeneration, cognitive and motor impairment....

Obstructive sleep apnoea (OSA) is characterized by repetitive collapse (apnoea) or partial collapse (hypopnoea) of the pharyngeal airway during sleep...

The Mediator complex with its catalytic subunit the Mediator kinase module, composed of CDK8/19 and other members, is multimeric complex regulating...
Supervisor: Dr Marius Dannappel

HIV infection has a substantial impact on immune cells, and whilst many of these effects are improved after starting anti-HIV therapy, they are often...
Supervisor: Dr Anna Hearps

Inflammation in the lung is critical for host defence against viruses. However, excessive inflammation and immunopathology are characteristic...

Self-reactive T cells cause many autoimmune diseases, and can also trigger serious autoimmune side-effects in cancer patients undergoing...

We manage the Australian Autoinflammatory Disease Registry (AADRY.org), and collaborate widely to identify genetic variants that may be the cause of...
Supervisor: Prof Seth Masters

Incomplete reporting of systematic reviews prevents users of the report from being able to fully interpret the findings and understand the...
Supervisor: Dr Matthew Page

Inflammatory Bowel Disease (IBD), predominantly Crohn’s Disease (CD) and Ulcerative Colitis (UC), is a chronic inflammatory condition of unknown...
Supervisor: A/Prof Edward Giles

Our laboratory has a major interest in breast cancer, particularly the triple negative/basal breast cancer subtype, which is associated with poor...
Supervisor: Professor Roger Daly

Congenital syphilis, caused by mother to child transmission of syphilis, is the second leading cause of stillbirth globally. Definitive diagnosis of...
Supervisor: Dr Minh Pham

As malaria transmission continues to decline, even the most sensitive methods for determining prevalence via detection of the parasite become...

Two key pathways controlling amino acid homeostasis are the cellular sensors mTOR and GCN2 but these cannot be the only ones. Here using cell based...
Supervisor: Dr Adam Rose

Stroke is a global leading cause of death and disability. Despite this, there is currently no treatment to limit inflammatory events which has been...

The formation of the head and face is a tightly regulated process, with variations from the genetic program leading to craniofacial defects. We have...
Supervisor: Dr. Jan Manent

Parkinson's disease (PD) is a debilitating neurodegenerative disorder that affects over 7 million people worldwide. Hallmark symptom of PD is...
Supervisor: Dr Joohyung Lee

Cardiovascular diseases (CVDs), principally ischemic heart disease including myocardial infarction (heart attacks) and stroke, are the leading cause...

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