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Research Projects

The Hippo/YAP signalling pathway is frequently dysregulated (~80%) in breast cancer. Yet, efforts aimed at targeting this pathway for therapeutic...
Supervisor: Dr Lan Nguyen

Diversity is one of the most highly evaluated value in our workplace to maximize its performance. Diversity in neural cells (neurons) may be...
Supervisor: Dr Tatsuo Sato

Anti-mullerian Hormone (AMH) or Mullerian Inhibiting Substance (MIS) is fundamentally known for its crucial activities in gonadal development during...
Supervisor: Dr Kelly Walton

The treatment of bacterial infections in humans and animals has largely relied on the use of antibiotics for over 70 years. One consequence of the...
Supervisor: Professor Dena Lyras

The control of stem cell division and differentiation is crucial to ensure correct development of an embryo and to maintain tissue homeostasis during...

This project ewill fucntionally analyse novel genes found to be expressed in embryonic chicken gonads. Methods include standard and cutting edge...

The human genome is dominated by non-protein encoding information. Indeed, the differences between humans and other animals cannot be accounted for...

Small cell lung cancer (SCLC) is an incredibly aggressive form of lung cancer with limited treatment options, begging the need for major therapeutic...

Our group focuses of studying dendritic cells (DC) by analysing the cell surface receptors they express with the view that these receptors contribute...

The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...

The eukaryotic genome consists of two classes of genes preceded by distinctly different promoter sequences. Housekeeping genes (90%) code for...
Supervisor: Dr Hans Elmlund

Gastric cancer is a leading cause of cancer-related death, claiming more than 1 million lives annually. A major predisposing factor to developing...
Supervisor: Dr Dustin Flanagan

The U.S. Food and Drug Administration (FDA) designated psilocybin as a “breakthrough therapy” in 2018 based on its efficacy in treatment-resistant...
Supervisor: Dr Claire Foldi

Developing tumour cells interact with a complex and heterogeneous ecosystem, namely the tumour microenvironment (TME), comprising mutant and wild-...
Supervisor: Dr Dustin Flanagan

This exciting project will use genetic techniques to identify mechanisms that control brain development in the Caenorhabditis elegans model. The C....

Hunger can tune our sense of smell to help find food, identify foods high in calories and affect memories associated with food. Currently, we do not...

Our ability to recover from injury is crucial for survival. The mechanism by which plasminogen promotes wound healing is poorly understood. It is...
Supervisor: Dr Ruby Law

Group A Streptococcus hijacks host plasminogen to facilitate colonization and dissemination. This infection can lead to life-threatening infections...
Supervisor: Dr Ruby Law

Persistent hunger-sensing in the absence of food availability serves to promote adaptive behaviours that enable food seeking in potentially novel and...

Despite current diabetes management, patients with glucose-lowering therapies often deal with hypoglycemia, a condition with abnormally low blood...

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